Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18640752 | 0.82 | HTT (1.00) | HTTMAPTALDH1A1KDM4EGAA | |
| SCHEMBL11442714 | 0.78 | HPGD (0.59) | HTTMAPTALDH1A1HPGDPOLB | |
| SCHEMBL30772996 | 0.77 | HTT (0.71) | HTTMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL27345451 | 0.77 | HTT (0.71) | HTTMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL9502644 | 0.77 | HTT (0.71) | HTTMAPTALDH1A1KDM4EPOLB | |
| SCHEMBL5946852 | 0.76 | MAPT (0.60) | HTTMAPTALDH1A1KDM4EGAA | |
| SCHEMBL12478850 | 0.75 | HTT (0.53) | HTTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL28000002 | 0.74 | HTT (0.67) | HTTMAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30084823 | 0.73 | RAB9A (0.55) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL2891499 | 0.73 | RAB9A (0.55) | MAPTALDH1A1KDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015060378-A1 | AMINOPYRIDINE DERIVATIVE AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE | 日本曹達株式会社 | 2015-04-30 | — | — | WO | disclosed |