Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12027664 | 1.00 | KDM1A (0.33) | KDM1AL3MBTL1NCF1 | |
| SCHEMBL3589693 | 0.78 | NCF1 (0.33) | NCF1 | |
| SCHEMBL13236308 | 0.72 | LMNA (0.44) | — | |
| SCHEMBL3425370 | 0.72 | L3MBTL1 (0.40) | L3MBTL1 | |
| SCHEMBL20322474 | 0.72 | HRH3 (0.33) | — | |
| SCHEMBL1488427 | 0.72 | NCF1 (0.52) | KDM1AL3MBTL1NCF1 | |
| SCHEMBL12731255 | 0.72 | IRAK4 (0.33) | L3MBTL1 | |
| SCHEMBL12731252 | 0.72 | IRAK4 (0.33) | L3MBTL1 | |
| SCHEMBL13943104 | 0.72 | IRAK4 (0.33) | L3MBTL1 | |
| SCHEMBL12731254 | 0.72 | IRAK4 (0.33) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188251-B1 | ARYLSULFONAMIDES WITH ANALGESIC ACTIVITY | BOEHRINGER INGELHEIM INT (DE) | 2015-04-29 | — | — | EP | disclosed |