Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP14 | P54578 | 1/20 | 0.37 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667597 | 1.00 | ELANE (0.38) | ELANEKDM4EUSP14KDM4DFEN1 | |
| SCHEMBL1667600 | 1.00 | ELANE (0.38) | ELANEKDM4EUSP14KDM4DFEN1 | |
| SCHEMBL1667769 | 0.87 | ELANE (0.39) | ELANEKDM4EUSP14KDM4DFEN1 | |
| SCHEMBL1075173 | 0.80 | ALDH1A1 (0.40) | KDM4EUSP14PPARG | |
| SCHEMBL1075175 | 0.80 | ALDH1A1 (0.40) | KDM4EUSP14PPARG | |
| SCHEMBL1075176 | 0.80 | ALDH1A1 (0.40) | KDM4EUSP14PPARG | |
| SCHEMBL1667574 | 0.80 | FEN1 (0.40) | KDM4EFEN1PPARGPDE4APDE4B | |
| SCHEMBL1667571 | 0.80 | FEN1 (0.40) | KDM4EFEN1PPARGPDE4APDE4B | |
| SCHEMBL12797903 | 0.80 | FEN1 (0.34) | FEN1APPPPARGPDE4APDE4B | |
| SCHEMBL1667570 | 0.80 | FEN1 (0.40) | KDM4EFEN1PPARGPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | claimed |
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |