Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 10/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP14 | P54578 | 1/20 | 0.37 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667597 | 0.87 | ELANE (0.38) | ELANEKDM4EUSP14KDM4DFEN1 | |
| SCHEMBL1667600 | 0.87 | ELANE (0.38) | ELANEKDM4EUSP14KDM4DFEN1 | |
| SCHEMBL1667598 | 0.87 | ELANE (0.38) | ELANEKDM4EUSP14KDM4DFEN1 | |
| SCHEMBL1667576 | 0.80 | KDM4E (0.41) | ELANEKDM4EUSP14KDM4DFEN1 | |
| SCHEMBL1667703 | 0.78 | USP14 (0.41) | ELANEKDM4EUSP14KDM4DFEN1 | |
| SCHEMBL1667847 | 0.76 | USP14 (0.46) | ELANEKDM4EUSP14FEN1KCNMA1 | |
| SCHEMBL1667677 | 0.75 | NTRK1 (0.34) | USP14FEN1PPARGPDE4APDE4B | |
| SCHEMBL1667676 | 0.75 | NTRK1 (0.34) | USP14FEN1PPARGPDE4APDE4B | |
| SCHEMBL1667678 | 0.75 | FEN1 (0.33) | USP14FEN1PPARGPDE4APDE4B | |
| SCHEMBL1667710 | 0.74 | USP14 (0.39) | ELANEKDM4EUSP14KDM4DPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | claimed |