Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15398290 | 0.78 | CHRM1 (0.33) | — | |
| SCHEMBL14252461 | 0.76 | CPB2 (0.31) | — | |
| SCHEMBL19038578 | 0.73 | — | — | |
| SCHEMBL17404777 | 0.71 | CA1 (0.38) | CA1CA2 | |
| SCHEMBL25317082 | 0.70 | CA2 (0.58) | CA1CA2 | |
| SCHEMBL13482801 | 0.70 | — | — | |
| SCHEMBL13539959 | 0.70 | — | — | |
| SCHEMBL15525400 | 0.70 | — | — | |
| SCHEMBL16684312 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL23923852 | 0.68 | PTGS1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225213-B1 | TRIAZOLE-SUBSTITUTED ARYLAMIDE DERIVATIVES AND THEIR USE AS P2X3 AND /OR P2X2/3 PURINERGIC RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2015-04-29 | — | — | EP | disclosed |