SCHEMBL25317082

SCHEMBL25317082

CCC(CCCN=[N+]=[N-])C(N)=O

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ CA2 P00918 6/20 0.58
▸ CA1 P00915 4/20 0.58
▸ MAPK1 P28482 1/20 0.37
▸ NOS1 P29475 5/20 0.34
▸ NOS2 P35228 4/20 0.34
▸ NOS3 P29474 3/20 0.34
▸ CPN1 P15169 1/20 0.34
▸ CPB2 Q96IY4 1/20 0.34
▸ DDAH1 O94760 3/20 0.33
▸ CYP2C19 P33261 2/20 0.33
▸ THPO P40225 1/20 0.33
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15995454 0.84 CA2 (0.57) CA2CA1MAPK1NOS1CPN1
SCHEMBL16013208 0.76 DDAH1 (0.31) NOS1NOS2DDAH1CYP2C19
Hydrochloric Acid SCHEMBL28639611 0.76 CA1 (0.34) CA2CA1NOS1NOS2CPB2
SCHEMBL24295447 0.75 CTSL (0.34) CA2CA1NOS1DDAH1
SCHEMBL376915 0.74 CA2 (1.00) CA2CA1MAPK1MEN1KMT2A
SCHEMBL7038841 0.74 CA2 (1.00) CA2CA1MAPK1MEN1KMT2A
SCHEMBL277393 0.72 CA2 (0.87) CA2CA1MAPK1
SCHEMBL9542331 0.72 CA2 (0.95) CA2CA1MAPK1MEN1KMT2A
SCHEMBL6445932 0.72 CA2 (0.95) CA2CA1MAPK1MEN1KMT2A
SCHEMBL5446281 0.72 CA2 (0.72) CA2CA1MAPK1CYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260077073-A1 GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR)-TARGETED COMPOUNDS AND USES THEREOF ALPHA 9 ONCOLOGY INC (CA) 2026-03-19 — — US disclosed
US-20250195702-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2025-06-19 — — US disclosed
US-20250186627-A1 RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2025-06-12 — — US disclosed
US-20250161501-A1 Radiolabeled Compounds for Imaging of Fibroblast Activation Protein (FAP) and Treatment of FAP-Related Disorders PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2025-05-22 — — US disclosed
WO-2025054727-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2025-03-20 — — WO disclosed
US-12246076-B2 Radiolabeled compounds for in vivo imaging of gastrin-releasing peptide receptor (GRPR) and treatment of GRPR-related disorders PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2025-03-11 — — US disclosed
EP-4499663-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS Provincial Health Services Authority (CA) 2025-02-05 — — EP disclosed
EP-4486756-A1 RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN Provincial Health Services Authority (CA) 2025-01-08 — — EP disclosed
CN-119213011-A Radiolabeled compounds for in vivo imaging of the Gastrin Releasing Peptide Receptor (GRPR) and treatment of GRPR-related disorders 省卫生服务机构 2024-12-27 — — CN disclosed
US-20240123099-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2024-04-18 — — US disclosed
WO-2023178449-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2023-09-28 — — WO disclosed
WO-2023164775-A1 RADIOLABELED COMPOUNDS TARGETNG THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2023-09-07 — — WO disclosed
WO-2023133645-A1 RADIOLABELED COMPOUNDS FOR IMAGING OF FIBROBLAST ACTIVATION PROTEIN (FAP) AND TREATMENT OF FAP-RELATED DISORDERS PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2023-07-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250186627-A1 RADIOLABELED COMPOUNDS TARGETING THE PROSTATE-SPECIFIC MEMBRANE ANTIGEN FSHR, ESRRA, ESRRG CA2 2307/4885CA1 1092/4885MAPK1 3051/4885
US-20250161501-A1 Radiolabeled Compounds for Imaging of Fibroblast Activation Protein (FAP) and Treatment of FAP-Related Disorders FAP, FIBP, FGFR1 CA2 888/4885CA1 3221/4885MAPK1 1712/4885
US-12246076-B2 Radiolabeled compounds for in vivo imaging of gastrin-releasing peptide receptor (GRPR) and treatment of GRPR-related disorders GRPR, NPY5R, NPY2R CA2 1162/4885CA1 209/4885MAPK1 3874/4885
US-20240123099-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS GRPR, NPY5R, NPY2R CA2 1162/4885CA1 209/4885MAPK1 3874/4885
US-20250195702-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS GRPR, NPY5R, NPY2R CA2 1083/4885CA1 210/4885MAPK1 4024/4885
US-20260077073-A1 GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR)-TARGETED COMPOUNDS AND USES THEREOF GRPR, GIPR, GLP1R CA2 311/4885CA1 104/4885MAPK1 2432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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