SCHEMBL166790

SCHEMBL166790

CC(=C(CC(=O)O)C(=O)O)C1CCCC1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.36
HSD17B10 Q99714 1/20 0.36
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
EPHX1 P07099 1/20 0.33
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
NAAA Q02083 1/20 0.33
ALDH1A1 P00352 1/20 0.32
OPRD1 P41143 1/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
KMT2A Q03164 1/20 0.32
LDHA P00338 1/20 0.31
SRR Q9GZT4 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9354742 0.98 CES2 (0.38) SMN1; SMN2HSD17B10CES2CES1HDAC8
SCHEMBL16879331 0.87 NAAA (0.33) CES2CES1HDAC8HDAC6EPHX1
SCHEMBL28712744 0.80 CES2 (0.39) CES2CES1HDAC8HDAC6EPHX1
SCHEMBL6514901 0.79 SMN1; SMN2 (0.33) SMN1; SMN2HSD17B10CES2CES1HDAC8
SCHEMBL6522206 0.79 SMN1; SMN2 (0.33) SMN1; SMN2HSD17B10CES2CES1HDAC8
SCHEMBL162618 0.76 NAAA (0.37) SMN1; SMN2HSD17B10CES2CES1HDAC8
SCHEMBL6515569 0.74 HDAC8 (0.33) SMN1; SMN2HSD17B10CES2CES1HDAC8
SCHEMBL6516569 0.73 CES2 (0.37) SMN1; SMN2HSD17B10CES2CES1HDAC8
SCHEMBL6519783 0.73 HDAC8 (0.32) SMN1; SMN2HSD17B10CES2CES1HDAC8
SCHEMBL6519507 0.73 EPHX2 (0.35) SMN1; SMN2HSD17B10LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2145921-B1 Vulcanizable polymer compositions ARLANXEO DEUTSCHLAND GMBH (DE) 2017-01-25 EP claimed
EP-2199326-B1 Vulcanizable polymer compositions LANXESS DEUTSCHLAND GMBH (DE) 2014-10-29 EP claimed
WO-2025047819-A1 AQUEOUS DISPERSION OF NITRILE RUBBER PARTICLES 日本ゼオン株式会社 2025-03-06 WO disclosed
WO-2025028232-A1 CROSSLINKABLE RUBBER COMPOSITION, CROSSLINKED RUBBER OBJECT, AND SEALING MATERIAL 日本ゼオン株式会社 2025-02-06 WO disclosed
WO-2025009411-A1 NITRILE RUBBER COMPOSITION AND CROSSLINKED MOLDED BODY 日本ゼオン株式会社 2025-01-09 WO disclosed
EP-3728355-B1 NITRILE DIENE CARBOXYLIC ACID ESTER COPOLYMERS ARLANXEO DEUTSCHLAND GMBH (DE) 2022-04-20 EP disclosed
EP-3668922-B1 VULCANISABLE COMPOSITIONS CONTAINING HYDROGENATED NITRILE RUBBER, VULCANIZATES PREPARED FROM SAME AND THEIR USE ARLANXEO DEUTSCHLAND GMBH (DE) 2022-03-16 EP disclosed
EP-3720885-B1 METHOD FOR PRODUCING NITRILE RUBBERS WITH RUTHENIUM COMPLEX CATALYSTS ARLANXEO DEUTSCHLAND GMBH (DE) 2021-12-01 EP disclosed
EP-3684604-B1 VULCANIZABLE HNBR COMPOSITION WITH HIGH THERMAL CONDUCTIVITY ARLANXEO DEUTSCHLAND GMBH (DE) 2021-11-24 EP disclosed
EP-3533826-B1 CROSSLINKABLE RUBBER COMPOSITION, RUBBER CROSSLINKED PRODUCT, AND COMPOSITE ZEON CORP (JP) 2021-10-06 EP disclosed
US-10865293-B2 Cross-linkable rubber composition, rubber crosslinked product, and complex ZEON CORPORATION (JP) 2020-12-15 US disclosed
EP-2325237-A1 Stable fine-particle suspensions of functionalised, wholly or partially hydrated nitrile rubbers LANXESS Deutschland GmbH (DE) 2011-05-25 EP disclosed
EP-2325238-A1 Stable fine-particle suspensions of functionalised, wholly or partially hydrated nitrile rubbers LANXESS Deutschland GmbH (DE) 2011-05-25 EP disclosed
EP-2316861-A1 Nitrile rubbers LANXESS Deutschland GmbH (DE) 2011-05-04 EP disclosed
EP-2316860-A1 Nitrile rubbers LANXESS Deutschland GmbH (DE) 2011-05-04 EP disclosed
EP-2298824-A1 Nitrile rubbers and production of same in organic solvents LANXESS Deutschland GmbH (DE) 2011-03-23 EP disclosed
EP-2289987-A1 Vulcanizable blend and its use for reparing rubberbased molded articles LANXESS Deutschland GmbH (DE) 2011-03-02 EP disclosed
EP-2267037-A1 Use of wholly or partially hydrated nitrile rubbers LANXESS Deutschland GmbH (DE) 2010-12-29 EP disclosed
US-20100168302-A1 Crosslinkable Rubber Composition and Cross-Linked Rubber ZEON CORPORATION (JP) 2010-07-01 US disclosed
EP-1964882-A1 CROSSLINKABLE RUBBER COMPOSITION AND RUBBER CROSSLINKED PRODUCT ZEON CORPORATION (JP) 2008-09-03 EP disclosed