Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL162618 | 0.92 | NAAA (0.37) | NAAAHDAC8HDAC6CES2CES1 | |
| SCHEMBL9354742 | 0.89 | CES2 (0.38) | NAAAHDAC8HDAC6CES2CES1 | |
| SCHEMBL166790 | 0.87 | SMN1; SMN2 (0.36) | NAAAHDAC8HDAC6CES2CES1 | |
| SCHEMBL6518902 | 0.81 | NAAA (0.34) | NAAAHDAC8HDAC6CES2CES1 | |
| SCHEMBL28712744 | 0.80 | CES2 (0.39) | NAAAHDAC8HDAC6CES2CES1 | |
| SCHEMBL6514901 | 0.79 | SMN1; SMN2 (0.33) | NAAAHDAC8HDAC6CES2CES1 | |
| SCHEMBL6515967 | 0.76 | CES2 (0.35) | NAAAHDAC8HDAC6CES2CES1 | |
| SCHEMBL6519420 | 0.76 | CES2 (0.35) | NAAAHDAC8HDAC6CES2CES1 | |
| SCHEMBL6520868 | 0.75 | ALDH1A1 (0.40) | L3MBTL1 | |
| SCHEMBL6519783 | 0.74 | HDAC8 (0.32) | HDAC8HDAC6CES2CES1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3090016-A1 | NITRILE-BUTADIENE RUBBERS THAT ARE STABLE IN STORAGE AND METHOD FOR PRODUCING SAME | ARLANXEO Deutschland GmbH (DE) | 2016-11-09 | — | — | EP | disclosed |
| WO-2015101600-A1 | NITRILE-BUTADIENE RUBBERS THAT ARE STABLE IN STORAGE AND METHOD FOR PRODUCING SAME | LANXESS DEUTSCHLAND GMBH (DE) | 2015-07-09 | — | — | WO | disclosed |