Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | CNR1 | P21554 | 3/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.53 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.53 |
| ▸ | TERT | O14746 | 3/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.51 |
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | PPARD | Q03181 | 3/20 | 0.51 |
| ▸ | PPARA | Q07869 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | FABP4 | P15090 | 2/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667902 | 1.00 | L3MBTL1 (0.56) | L3MBTL1KMT2AMEN1TDP1CNR1 | |
| SCHEMBL11543721 | 0.96 | CNR1 (0.59) | L3MBTL1TDP1CNR1CNR2PPARG | |
| SCHEMBL9806573 | 0.91 | CNR1 (0.49) | L3MBTL1KMT2AMEN1TDP1CNR1 | |
| SCHEMBL31429810 | 0.91 | CNR1 (0.64) | L3MBTL1KMT2AMEN1TDP1CNR1 | |
| SCHEMBL8971856 | 0.91 | L3MBTL1 (0.67) | L3MBTL1KMT2AMEN1TDP1GNAI3 | |
| SCHEMBL2982115 | 0.91 | L3MBTL1 (0.67) | L3MBTL1KMT2AMEN1TDP1GNAI3 | |
| SCHEMBL8972353 | 0.91 | L3MBTL1 (0.67) | L3MBTL1KMT2AMEN1TDP1GNAI3 | |
| SCHEMBL8971899 | 0.91 | L3MBTL1 (0.67) | L3MBTL1KMT2AMEN1TDP1GNAI3 | |
| SCHEMBL8973343 | 0.91 | L3MBTL1 (0.67) | L3MBTL1KMT2AMEN1TDP1GNAI3 | |
| SCHEMBL8972793 | 0.91 | L3MBTL1 (0.67) | L3MBTL1KMT2AMEN1TDP1GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10370344-B2 | 2-oxothiazole compounds and method of using same for chronic inflammatory disorders | AVEXXIN AS (NO) | 2019-08-06 | — | — | US | disclosed |
| EP-3431084-A1 | ANTIINFLAMMATORY 2-OXOTHIAZOLES | Avexxin AS (NO) | 2019-01-23 | — | — | EP | disclosed |
| US-20170166539-A1 | COMPOUND | AVEXXIN AS (NO) | 2017-06-15 | — | — | US | disclosed |
| US-9597318-B2 | 2-oxothiazole compounds and method of using same for chronic inflammatory disorders | AVEXXIN AS (NO) | 2017-03-21 | — | — | US | disclosed |
| EP-2482815-A1 | ANTI INFLAMMATORY 2-OXOTHIAZOLES AND 2 -OXOOXAZOLES | Avexxin AS (NO) | 2012-08-08 | — | — | EP | disclosed |
| US-20110136879-A1 | COMPOUND | AVEXXIN AS (NO) | 2011-06-09 | — | — | US | disclosed |
| WO-2011039365-A1 | ANTI INFLAMMATORY 2-OXOTHIAZOLES AND 2 -OXOOXAZOLES | AVEXXIN AS (NO) | 2011-04-07 | — | — | WO | disclosed |
| US-4144256-A | FATTY AMIDE SUBSTITUTED WITH ACETYLTHIO GROUP OR GROUPS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1979-03-13 | — | — | US | disclosed |
| US-4092319-A | CARBOALKOXY-METHYLTHIO-FATTY AMIDE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1978-05-30 | — | — | US | disclosed |
| US-4062841-A | MICROBIOCIDE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1977-12-13 | — | — | US | disclosed |
| US-4061634-A | Sulfur-containing antimicrobial ester-amides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1977-12-06 | — | — | US | disclosed |
| US-4008137-A | FROM 10-UNDECENOYLMORPHOLINE AND A DIALKYL PHOSPHITE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1977-02-15 | — | — | US | disclosed |
| US-3996353-A | Phosphonated N,N-disubstituted fatty morpholines as bacterial and fungicidal agents | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1976-12-07 | — | — | US | disclosed |
| US-3988226-A | BY FREE RADICAL ADDITION OF DIALKYL PHOSPHITES TO THE N,N-DISUBSTITUTED AMIDES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1976-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136879-A1 | COMPOUND | CBR1, CBR3, CCR1 | L3MBTL1 757/4885KMT2A 4796/4885MEN1 2321/4885 |
| US-20170166539-A1 | COMPOUND | CBR1, CBR3, CCR1 | L3MBTL1 753/4885KMT2A 4797/4885MEN1 2314/4885 |
| US-10370344-B2 | 2-oxothiazole compounds and method of using same for chronic inflammatory disorders | CX3CR1, LTC4S, CBR1 | L3MBTL1 351/4885KMT2A 4706/4885MEN1 3221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.