Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3BCHECHRM1CHRM2CHRM3CHRM4CHRNA3CHRNA4CHRNB2CHRNB4ESR1ESR2GABRA1GABRB1GABRG2GBA1GHSRHRH1HTR1DHTR2AMAOBOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8UGCGrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL119095 | 1.00 | TSHR (0.47) | TSHRLMNACA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL17500033 | 1.00 | TSHR (0.47) | TSHRLMNACA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL29371410 | 0.96 | TSHR (0.44) | TSHRLMNACA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL3160181 | 0.96 | LMNA (0.48) | TSHRLMNACA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL27988970 | 0.96 | TSHR (0.44) | TSHRLMNACA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL3401660 | 0.96 | TSHR (0.44) | TSHRLMNACA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL5801093 | 0.96 | LMNA (0.48) | TSHRLMNACA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL3404570 | 0.96 | TSHR (0.44) | TSHRLMNACA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL11878569 | 0.96 | TSHR (0.44) | TSHRLMNACA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL27988969 | 0.96 | TSHR (0.44) | TSHRLMNACA4CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109568652-A | Promote the dressing composition of wound healing | 粤肽生物科技(珠海)有限公司 | 2019-04-05 | — | — | CN | disclosed |
| CN-104488963-B | Compound composition with methanesulphonyl myclobutanil and organic copper bactericide and preparation | 广西田园生化股份有限公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-104271676-B | Comprising the piece shape effect pigment containing copper coating, Its Preparation Method And Use | 埃卡特有限公司 | 2017-03-15 | — | — | CN | disclosed |
| US-9127165-B2 | Plate-shaped effect pigment comprising a copper-containing coating, method for the production thereof, and use thereof | ECKART GMBH (DE) | 2015-09-08 | — | — | US | disclosed |
| US-20150122146-A1 | Plate-Shaped Effect Pigment Comprising a Copper-Containing Coating, Method for the Production Thereof, and Use Thereof | ECKART GMBH (DE) | 2015-05-07 | — | — | US | disclosed |
| CN-104488963-A | Compound composition with methanesulphonyl myclobutanil and organic copper bactericide and preparation | GAUNGXI TIANYUAN BIOCHEMISTRY | 2015-04-08 | — | — | CN | disclosed |
| CN-104271676-A | Plate-shaped effect pigment comprising a coating containing copper, method for the production thereof, and use thereof | ECKART GMBH | 2015-01-07 | — | — | CN | disclosed |