Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3BCHECHRM1CHRM2CHRM3CHRM4CHRNA3CHRNA4CHRNB2CHRNB4ESR1ESR2GABRA1GABRB1GABRG2GBA1GHSRHRH1HTR1DHTR2AMAOBOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8UGCGrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CA4 | P22748 | 4/20 | 0.43 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL10629197 | 0.96 | LMNA (0.46) | LMNATSHRCA4FAHD1CA1 | |
| Cadaverine Tartrate SCHEMBL6048227 | 0.96 | CA4 (0.47) | LMNATSHRCA4FAHD1CA1 | |
| Cadaverine Tartrate SCHEMBL16680320 | 0.96 | TSHR (0.47) | LMNATSHRCA4FAHD1CA1 | |
| Cadaverine Tartrate SCHEMBL17500033 | 0.96 | TSHR (0.47) | LMNATSHRCA4FAHD1CA1 | |
| Cadaverine Tartrate SCHEMBL119095 | 0.96 | TSHR (0.47) | LMNATSHRCA4FAHD1CA1 | |
| Cadaverine Tartrate SCHEMBL24913 | 0.96 | LMNA (0.50) | LMNATSHRCA4FAHD1CA1 | |
| Cadaverine Tartrate SCHEMBL409591 | 0.96 | LMNA (0.50) | LMNATSHRCA4FAHD1CA1 | |
| Cadaverine Tartrate SCHEMBL29483921 | 0.96 | LMNA (0.50) | LMNATSHRCA4FAHD1CA1 | |
| Cadaverine Tartrate SCHEMBL30052254 | 0.96 | LMNA (0.50) | LMNATSHRCA4FAHD1CA1 | |
| Cadaverine Tartrate SCHEMBL27709522 | 0.93 | LMNA (0.44) | LMNATSHRCA4FAHD1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006068977-A2 | STORAGE STABLE, CONCENTRATED, COPPER CONTAINING LIQUID DYE SOLUTIONS | KEMIRA OYJ (FI) | 2006-06-29 | — | — | WO | disclosed |
| US-6903197-B2 | Azoxy dyes and copper complexes thereof | BASF AKTIENGESELLSCHAFT (DE) | 2005-06-07 | — | — | US | disclosed |
| US-20040204570-A1 | Azoxy dyes and copper complexes thereof | BASF AKIENGESELLSCHAFT (DE) | 2004-10-14 | — | — | US | disclosed |
| US-6727351-B1 | COMPLEXING, COUPLING, AND DEACYLATION | BASF AKTIENGESELLSCHAFT (DE) | 2004-04-27 | — | — | US | disclosed |
| US-6521032-B1 | Inks yield magenta prints and dyeings having good fastness to light and high color brilliance | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-02-18 | — | — | US | disclosed |
| CN-1101176-C | Polyol composition, process for its preparation and its applications | ROQUETTE FRERES (FR) | 2003-02-12 | — | — | CN | disclosed |
| US-5773604-A | HEAT RESISTANT POLYOLS WITH CHEMICAL STABILITY | ROQUETTE FRERES (FR) | 1998-06-30 | — | — | US | disclosed |
| CN-1130502-A | Polyol composition, process for its preparation and its applications | ROQUETTE FRERES (FR) | 1996-09-11 | — | — | CN | disclosed |
| US-4515599-A | COLORFAST BLUE SHADES | CIBA GEIGY CORPORATION (US) | 1985-05-07 | — | — | US | disclosed |
| US-4283331-A | FIBER-REACTIVE DYES | CIBA-GEIGY CORPORATION (US) | 1981-08-11 | — | — | US | disclosed |
| US-4270918-A | METALLIZED TRIAZINE-FUNCTIONAL MONOAZO DYE | CIBA-GEIGY CORPORATION (US) | 1981-06-02 | — | — | US | disclosed |
| US-4001203-A | Heavy metal complexes of azo dyestuffs containing a heterocyclic diazo component and the residue of 5-halogeno-2,3-dihydrozypyridine as coupling component | CIBA-GEIGY AG (CH) | 1977-01-04 | — | — | US | disclosed |
| US-4001205-A | WATER-SOLUBLE, FIBER-REACTIVE PHENYLAZODIHYDROXY, METHYL, CYANOPYRIDINE DYESTUFFS | CIBA-GEIGY AG (CH) | 1977-01-04 | — | — | US | disclosed |
| US-3956263-A | 4-Methyl-2,6-dihydroxy-3-cyanopyridine containing dyestuffs | CIBA-GEIGY AG (CH) | 1976-05-11 | — | — | US | disclosed |