Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL501048 | 0.76 | ALDH1A1 (0.41) | MAPK1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL500990 | 0.67 | SMN1; SMN2 (0.40) | MAPK1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL16680651 | 0.65 | SMN1; SMN2 (0.54) | MAPK1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL22433209 | 0.62 | ALDH1A1 (0.69) | MAPK1ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL14367365 | 0.61 | KMT2A (0.70) | KMT2ALMNAMAPTPOLBRAB9A | |
| SCHEMBL16249234 | 0.61 | ALDH1A1 (0.63) | MAPK1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL1913783 | 0.60 | ACHE (0.49) | MAPK1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL1629001 | 0.60 | HSP90AA1 (0.49) | MAPK1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL15726878 | 0.60 | ALDH1A1 (0.64) | MAPK1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7659574 | 0.59 | PKM (0.61) | ALDH1A1KMT2ALMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150126499-A1 | Triazole Compounds that Modulate HSP90 Activity | SYNTA PHARMACEUTICALS CORP (US) | 2015-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150126499-A1 | Triazole Compounds that Modulate HSP90 Activity | HSP90AB1, HSP90B1, HSP90AA1 | MAPK1 1405/4885ALDH1A1 2145/4885MEN1 4432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.