SCHEMBL16684147

SCHEMBL16684147

O=S(=O)(NCPO)c1cc2cc(OCCCl)cc(Cl)c2s1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
LGALS8 O00214 2/20 0.30
LGALS3 P17931 2/20 0.30
LGALS1 P09382 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3483174 0.83
SCHEMBL3483171 0.83
SCHEMBL3483589 0.78 CA2 (0.39)
SCHEMBL3483426 0.69
SCHEMBL4215129 0.65 CA2 (0.39) ALDH1A1
SCHEMBL3483371 0.64 CA2 (0.38)
SCHEMBL14943011 0.64 TRPV4 (0.38)
SCHEMBL3483784 0.64 CA2 (0.38)
SCHEMBL3483419 0.62 PFKFB4 (0.41) ALDH1A1LGALS8LGALS3
SCHEMBL3484161 0.62 PFKFB4 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2049200-B1 NOVEL INHIBITORS OF BETA-LACTAMASE METHYLGENE INC (CA) 2015-04-29 EP disclosed