Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 6/20 | 0.33 |
| ▸ | AR | P10275 | 6/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14943023 | 0.89 | PLA2G7 (0.35) | PLA2G7ARSLC22A12 | |
| SCHEMBL3483626 | 0.85 | AR (0.30) | AR | |
| SCHEMBL14943085 | 0.81 | TRPV4 (0.37) | — | |
| SCHEMBL13031933 | 0.78 | CA2 (0.33) | PLA2G7ARSLC22A12 | |
| SCHEMBL3483884 | 0.77 | S1PR1 (0.31) | SLC22A12 | |
| SCHEMBL16684160 | 0.76 | BLM (0.36) | PLA2G7ARSLC22A12 | |
| SCHEMBL13031941 | 0.75 | TRPV4 (0.32) | ARSLC22A12 | |
| SCHEMBL16684157 | 0.75 | TRPV4 (0.34) | — | |
| SCHEMBL13031927 | 0.74 | CA2 (0.32) | PLA2G7ARSLC22A12 | |
| SCHEMBL13072844 | 0.74 | CA2 (0.31) | PLA2G7ARSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049200-B1 | NOVEL INHIBITORS OF BETA-LACTAMASE | METHYLGENE INC (CA) | 2015-04-29 | — | — | EP | disclosed |