Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 8/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13031987 | 0.94 | SLC22A12 (0.34) | PLA2G7ARSLC22A12TRPV4 | |
| Trifluoroacetic Acid SCHEMBL3948690 | 0.91 | PLA2G7 (0.34) | PLA2G7ARSLC22A12TRPV4 | |
| SCHEMBL14943082 | 0.91 | SLC22A12 (0.34) | PLA2G7ARSLC22A12TRPV4 | |
| Trifluoroacetic Acid SCHEMBL4158728 | 0.87 | CACNA1B (0.36) | PLA2G7ARSLC22A12 | |
| SCHEMBL13032081 | 0.86 | TRPV4 (0.36) | PLA2G7ARSLC22A12TRPV4 | |
| SCHEMBL13031985 | 0.85 | TRPV4 (0.36) | TRPV4 | |
| SCHEMBL16684145 | 0.84 | AR (0.33) | PLA2G7ARTRPV4 | |
| SCHEMBL16684158 | 0.83 | CYP1A2 (0.32) | AR | |
| SCHEMBL14942995 | 0.83 | CYP1A2 (0.32) | AR | |
| SCHEMBL14943083 | 0.81 | TRPV4 (0.36) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049200-B1 | NOVEL INHIBITORS OF BETA-LACTAMASE | METHYLGENE INC (CA) | 2015-04-29 | — | — | EP | disclosed |