⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL504610 | 0.87 | LMNA (0.44) | — | |
| SCHEMBL6509721 | 0.87 | LMNA (0.44) | — | |
| SCHEMBL246685 | 0.87 | LMNA (0.44) | — | |
| SCHEMBL14124884 | 0.87 | LMNA (0.44) | — | |
| SCHEMBL346819 | 0.87 | LMNA (0.44) | — | |
| Water SCHEMBL6533488 | 0.85 | LMNA (0.42) | — | |
| Water SCHEMBL27487332 | 0.85 | LMNA (0.42) | — | |
| SCHEMBL14817456 | 0.84 | LMNA (0.37) | — | |
| Phosphoric Acid SCHEMBL21495145 | 0.81 | LMNA (0.39) | — | |
| SCHEMBL6287151 | 0.78 | LMNA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-10758557-B2 | Methods and compositions for treating hepatitis C virus | IDENIX PHARMACEUTICALS LLC (US) | 2020-09-01 | — | — | US | disclosed |
| US-20190290670-A1 | METHODS AND COMPOSITIONS FOR TREATING HEPATITIS C VIRUS | IDENIX PHARMACEUTICALS LLC (US) | 2019-09-26 | — | — | US | disclosed |
| US-10363265-B2 | Methods and compositions for treating hepatitis C virus | IDENIX PHARMACEUTICALS LLC (US) | 2019-07-30 | — | — | US | disclosed |
| EP-1292603-B1 | METHODS AND COMPOSITIONS FOR TREATING HEPATITIS C VIRUS | IDENIX PHARMACEUTICALS LLC (US) | 2017-02-22 | — | — | EP | disclosed |
| EP-1576138-B1 | 2'-METHYL NUCLEOSIDES IN COMBINATION WITH INTERFERON AND FLAVIVIRIDAE MUTATION | IDENIX PHARMACEUTICALS LLC (US) | 2017-02-01 | — | — | EP | disclosed |
| EP-1736478-B1 | Methods and compositions for treating flaviviruses and pestiviruses | IDENIX PHARMACEUTICALS INC (US) | 2015-07-22 | — | — | EP | disclosed |
| EP-2332952-B1 | Modified 2' and 3'-nucleoside prodrugs for treating flaviridae infections | IDENIX PHARMACEUTICALS INC (US) | 2015-04-29 | — | — | EP | disclosed |