SCHEMBL6287151

SCHEMBL6287151

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nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
GBA1 P04062 1/20 0.39
NLRP3 Q96P20 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6668228 1.00 LMNA (0.39) LMNAGBA1NLRP3
SCHEMBL16684264 0.78
SCHEMBL9571760 0.71
SCHEMBL28518390 0.71
SCHEMBL6509721 0.71 LMNA (0.44) LMNAGBA1NLRP3
SCHEMBL246685 0.71 LMNA (0.44) LMNAGBA1NLRP3
SCHEMBL14124884 0.71 LMNA (0.44) LMNAGBA1NLRP3
SCHEMBL346819 0.71 LMNA (0.44) LMNAGBA1NLRP3
SCHEMBL504610 0.71 LMNA (0.44) LMNAGBA1NLRP3
SCHEMBL27767293 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6846505-B2 Anti-oxidant DANISCO A/S (DK) 2005-01-25 US disclosed
US-20020051840-A1 Anti-oxidant DANISCO A/S (DK) 2002-05-02 US disclosed