SCHEMBL246685

SCHEMBL246685

O=C1CO[C@H](CO)[C@@H](O)[C@@H]1O

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
GBA1 P04062 1/20 0.44
NLRP3 Q96P20 1/20 0.33
PYGB P11216 3/20 0.33
TREH O43280 1/20 0.33
CDA P32320 5/20 0.32
PYGL P06737 1/20 0.32
PYGM P11217 1/20 0.32
LGALS3 P17931 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6509721 1.00 LMNA (0.44) LMNAGBA1NLRP3PYGBTREH
SCHEMBL504610 1.00 LMNA (0.44) LMNAGBA1NLRP3PYGBTREH
SCHEMBL346819 1.00 LMNA (0.44) LMNAGBA1NLRP3PYGBTREH
SCHEMBL14124884 1.00 LMNA (0.44) LMNAGBA1NLRP3PYGBTREH
Water SCHEMBL6533488 0.98 LMNA (0.42) LMNAGBA1NLRP3PYGBTREH
Water SCHEMBL27487332 0.98 LMNA (0.42) LMNAGBA1NLRP3PYGBTREH
Phosphoric Acid SCHEMBL21495145 0.93 LMNA (0.39) LMNAGBA1NLRP3TREH
SCHEMBL16684264 0.87
SCHEMBL6531031 0.84 LMNA (0.35) LMNAGBA1
SCHEMBL14817456 0.80 LMNA (0.37) LMNAGBA1NLRP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250017950-A1 COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS UCL BUSINESS LTD (GB) 2025-01-16 US claimed
US-12137706-B2 Micro-encapsulated aquaculture feed SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. (JP) 2024-11-12 US claimed
EP-4433077-A1 COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS UCL Business Ltd (GB) 2024-09-25 EP claimed
WO-2023089313-A1 COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS UCL BUSINESS LTD (GB) 2023-05-25 WO claimed
WO-2022059694-A1 COMPOSITION FOR IMPROVING RENAL FUNCTION 国立大学法人鹿児島大学 2022-03-24 WO claimed
EP-3504174-A1 METHOD FOR THE PRODUCTION OF GLYCOLS FROM AN ANHYDROSUGAR FEED Shell Internationale Research Maatschappij B.V. (NL) 2019-07-03 EP claimed
US-20190194100-A1 METHOD FOR THE PRODUCTION OF GLYCOLS FROM AN ANHYDROSUGAR FEED SHELL OIL COMPANY 2019-06-27 US claimed
CN-108034694-B A kind of detection kit and its detection method of 1,5- anhydro sorbitol 广州市进德生物科技有限公司 2019-01-04 CN claimed
CN-108034694-A A kind of detection kit and its detection method of 1,5- anhydro sorbitols 广州市进德生物科技有限公司 2018-05-15 CN claimed
WO-2018039109-A1 METHOD FOR THE PRODUCTION OF GLYCOLS FROM AN ANHYDROSUGAR FEED SHELL OIL COMPANY (US) 2018-03-01 WO claimed
US-20030170832-A1 Ascopyrone P synthase DANISCO A/S (DK) 2003-09-11 US claimed
US-20030170829-A1 1,5-Anhydro-D-fructose dehydratase DANISCO A/S (DK) 2003-09-11 US claimed
WO-2003038085-A1 1,5-ANHYDRO-D-FRUCTOSE DEHYDRATASE DANISCO A/S (DK) 2003-05-08 WO claimed
WO-2003038084-A1 ASCOPYRONE P SYNTHASE DANISCO A/S (DK) 2003-05-08 WO claimed
WO-2003038107-A2 PROCESS FOR THE PRODUCTION OF ASCOPYRONE P DANISCO A/S (DK) 2003-05-08 WO claimed
WO-2003037918-A2 PYRANOSONE DEHYDRATASE FROM PHANEROCHAETE CHRYSOSPORIUM DANISCO A/S (DK) 2003-05-08 WO claimed
CN-1394142-A Use of cyclic ethers for the manufacture of a medicament for influencing glucose tolerance DANISCO (DK) 2003-01-29 CN claimed
US-5695970-A SUGAR SUBSTITUTES T&M BIOPOLYMER AKTIEBOLAG (SE) 1997-12-09 US claimed
EP-0665881-A1 A NEW GLUCAN LYASE PRODUCING 1,5-ANHYDROFRUCTOSE T & M BIOPOLYMER AKTIEBOLAG (SE) 1995-08-09 EP claimed
WO-1994009122-A1 A NEW GLUCAN LYASE PRODUCING 1,5-ANHYDROFRUCTOSE ALGATECH AB (SE) 1994-04-28 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190194100-A1 METHOD FOR THE PRODUCTION OF GLYCOLS FROM AN ANHYDROSUGAR FEED ALDOA, SORD, DERA LMNA 4599/4885GBA1 287/4885NLRP3 4422/4885
US-20030170832-A1 Ascopyrone P synthase COASY, DHPS, FDPS LMNA 2647/4885GBA1 3688/4885NLRP3 1508/4885
US-20250017950-A1 COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS POLRMT, TK2, GOT2 LMNA 2348/4885GBA1 498/4885NLRP3 3827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.