SCHEMBL16685

SCHEMBL16685

NC(=O)C[C@H](N)C(=O)NCC(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
MAPT P10636 2/20 0.45
LMNA P02545 1/20 0.45
PTGS2 P35354 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
PTGS1 P23219 1/20 0.41
GSTK1 Q9Y2Q3 1/20 0.41
ECE1 P42892 3/20 0.40
MME P08473 6/20 0.39
ACE P12821 3/20 0.39
CPA1 P15085 1/20 0.39
ACE2 Q9BYF1 1/20 0.39
BLM P54132 2/20 0.38
KMT2A Q03164 2/20 0.38
HPGD P15428 1/20 0.38
MAPK1 P28482 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MEN1 O00255 1/20 0.38
NPEPPS P55786 1/20 0.38
GLO1 Q04760 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3451522 1.00 ALDH1A1 (0.45) ALDH1A1MAPTLMNAPTGS2TDP1
Hydroxyamine SCHEMBL8490496 0.98 ALDH1A1 (0.44) ALDH1A1MAPTLMNAPTGS2TDP1
Glycine SCHEMBL1694000 0.94 ALDH1A1 (0.41) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL6136334 0.93 ALDH1A1 (0.40) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL7568157 0.93 ALDH1A1 (0.40) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL619330 0.93 ALDH1A1 (0.40) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL8346127 0.93 ALDH1A1 (0.40) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL8745360 0.93 ALDH1A1 (0.40) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL15499 0.93 ALDH1A1 (0.40) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL2189880 0.87 CA12 (0.35) ALDH1A1MAPTLMNAPTGS2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 76074 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250282824-A1 Inhibitors of the Wnt Signaling Pathway and Uses Thereof STICHTING VU (NL) 2025-09-11 US claimed
EP-4605013-A1 NOVEL ANTIBODY DRUG CONJUGATES WITH NOVEL NAPI2B ANTIBODIES, THERAPEUTIC METHODS AND USES THEREOF Tubulis GmbH (DE) 2025-08-27 EP claimed
EP-4605012-A2 NOVEL ANTI-NAPI2B ANTIBODIES AND ANTIBODY-DRUG-CONJUGATES BASED THEREON, THERAPEUTIC METHODS AND USES THEREOF Tubulis GmbH (DE) 2025-08-27 EP claimed
US-20250122311-A1 METHOD FOR HUMANIZING ANTIBODIES YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2025-04-17 US claimed
CN-118382639-A Humanized antibody method 耶达研究发展公司 2024-07-23 CN claimed
CN-118304317-A Preparation method of novel coronavirus inhibitor 段涵 2024-07-09 CN claimed
WO-2024143402-A1 DIETARY DIVERSITY EVALUATION METHOD 味の素株式会社 2024-07-04 WO claimed
US-20240190958-A1 NOVEL ANTIBODY DRUG CONJUGATES WITH NOVEL NAPI2B ANTIBODIES, THERAPEUTIC METHODS AND USES THEREOF TUBULIS GMBH (DE) 2024-06-13 US claimed
EP-4380976-A1 METHOD FOR HUMANIZING ANTIBODIES Yeda Research and Development Co. Ltd (IL) 2024-06-12 EP claimed
US-20240182596-A1 ANTI-NAPI2B ANTIBODIES AND ANTIBODY-DRUG-CONJUGATES BASED THEREON, THERAPEUTIC METHODS AND USES THEREOF TUBULIS GMBH (DE) 2024-06-06 US claimed
WO-1986003775-A1 DOG AND HORSE INTERFERONS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 1986-07-03 WO claimed
WO-1986002666-A1 METHODS FOR PROTEIN BINDING ENZYME COMPLEMENTATION ASSAYS MICROGENICS CORPORATION (US) 1986-05-09 WO claimed
US-4582800-A INTERFERON CLONED ONTO BACTERIA PLASMID HOFFMANN-LA ROCHE INC. (US) 1986-04-15 US claimed
EP-0166996-A1 A method for stabilizing a physiologically active substance produced by recombinant DNA technique and a stable aqueous solution or powder containing the same Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-01-08 EP claimed
WO-1985004397-A1 PLATELET RELATED GROWTH REGULATOR ONCOGEN (US) 1985-10-10 WO claimed
WO-1985004418-A1 VECTORS FOR THE EXPRESSION OF HIRUDINE, TRANSFORMED CELLS AND PROCESS FOR THE PREPARATION OF HIRUDINE TRANSGENE S.A. (FR) 1985-10-10 WO claimed
US-4544500-A POLYPEPTIDE SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1985-10-01 US claimed
EP-0118617-A2 Interleukin-2 polypeptides AJINOMOTO CO., INC. (JP) 1984-09-19 EP claimed
US-4457867-A VIRICIDES, ANTITUMOR ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-07-03 US claimed
US-4107298-A Antigenically active polypeptide and a process for its preparation AB BONNIERFORETAGEN (SE) 1978-08-15 US claimed