SCHEMBL8745360

SCHEMBL8745360

NC(=O)C[C@H](N)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
MAPT P10636 2/20 0.40
PTGS1 P23219 1/20 0.40
GSTK1 Q9Y2Q3 1/20 0.40
LMNA P02545 1/20 0.40
PTGS2 P35354 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ECE1 P42892 3/20 0.36
GLO1 Q04760 1/20 0.35
MME P08473 6/20 0.35
ACE P12821 3/20 0.35
CPA1 P15085 1/20 0.35
ACE2 Q9BYF1 1/20 0.35
HPGD P15428 1/20 0.34
MAPK1 P28482 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MEN1 O00255 1/20 0.34
BLM P54132 1/20 0.34
NPEPPS P55786 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6136334 1.00 ALDH1A1 (0.40) ALDH1A1MAPTPTGS1GSTK1LMNA
SCHEMBL8346127 1.00 ALDH1A1 (0.40) ALDH1A1MAPTPTGS1GSTK1LMNA
SCHEMBL15499 1.00 ALDH1A1 (0.40) ALDH1A1MAPTPTGS1GSTK1LMNA
SCHEMBL7568157 1.00 ALDH1A1 (0.40) ALDH1A1MAPTPTGS1GSTK1LMNA
SCHEMBL619330 1.00 ALDH1A1 (0.40) ALDH1A1MAPTPTGS1GSTK1LMNA
SCHEMBL3451522 0.93 ALDH1A1 (0.45) ALDH1A1MAPTPTGS1GSTK1LMNA
SCHEMBL16685 0.93 ALDH1A1 (0.45) ALDH1A1MAPTPTGS1GSTK1LMNA
Hydroxyamine SCHEMBL8490496 0.91 ALDH1A1 (0.44) ALDH1A1MAPTPTGS1GSTK1LMNA
SCHEMBL6129324 0.89 PTGS1 (0.46) PTGS1GSTK1GLO1MEN1KMT2A
SCHEMBL1442864 0.89 PTGS1 (0.46) PTGS1GSTK1GLO1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117136309-A Composition for differential diagnosis of malignant peripheral schwannoma 财团法人峨山社会福祉财团 2023-11-28 CN disclosed
CN-116710108-A Compositions and methods for simultaneous modulation of gene expression 维萨梅布有限公司 2023-09-05 CN disclosed
CN-111499758-B Method for screening human potassium ion channel modulators 中国科学院脑科学与智能技术卓越创新中心 2023-01-31 CN disclosed
CN-107847523-B Method for inducing cell division of postmitotic cells J·大卫格莱斯顿学会(根据J·大卫格莱斯顿意愿建立的遗嘱信托) 2022-03-11 CN disclosed
CN-113164555-A Compositions and methods for treating smooth muscle dysfunction 尤偌万科学有限公司 2021-07-23 CN disclosed
CN-112533959-A Harmless, structured scaffolds for structure-based amyloid disease vaccines and antigens 阿尔伯塔大学理事会 2021-03-19 CN disclosed
CN-111499758-A Method for screening human potassium ion channel modulators 中国科学院脑科学与智能技术卓越创新中心 2020-08-07 CN disclosed
CN-110709097-A Compositions and methods for treating idiopathic overactive bladder syndrome and detrusor overactivity 离子通道创新有限责任公司 2020-01-17 CN disclosed
CN-110462043-A The plant of character with modification COMMW SCIENT IND RES ORG 2019-11-15 CN disclosed
CN-107847523-A Method for inducing cell division of postmitotic cells J·大卫格莱斯顿学会(根据J·大卫格莱斯顿意愿建立的遗嘱信托) 2018-03-27 CN disclosed
CN-106852158-A Method for producing industrial products from vegetable lipids 联邦科学技术研究组织 2017-06-13 CN disclosed
EP-0755445-A1 CELL-CYCLE REGULATORY PROTEINS, AND USES RELATED THERETO COLD SPRING HARBOR LABORATORY (US) 1997-01-29 EP disclosed
WO-1995028483-A1 CELL-CYCLE REGULATORY PROTEINS, AND USES RELATED THERETO COLD SPRING HARBOR LABORATORY (US) 1995-10-26 WO disclosed