Sugi Predict

Sugi Predict / Compounds / SCHEMBL3451522

SCHEMBL3451522

SCHEMBL3451522

NC(=O)CC(N)C(=O)NCC(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.45
▸ MAPT P10636 2/20 0.45
▸ LMNA P02545 1/20 0.45
▸ PTGS2 P35354 1/20 0.45
▸ TDP1 Q9NUW8 1/20 0.45
▸ PTGS1 P23219 1/20 0.41
▸ GSTK1 Q9Y2Q3 1/20 0.41
▸ ECE1 P42892 3/20 0.40
▸ MME P08473 6/20 0.39
▸ ACE P12821 3/20 0.39
▸ CPA1 P15085 1/20 0.39
▸ ACE2 Q9BYF1 1/20 0.39
▸ BLM P54132 2/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ HPGD P15428 1/20 0.38
▸ MAPK1 P28482 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ NPEPPS P55786 1/20 0.38
▸ GLO1 Q04760 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16685 1.00 ALDH1A1 (0.45) ALDH1A1MAPTLMNAPTGS2TDP1
Hydroxyamine SCHEMBL8490496 0.98 ALDH1A1 (0.44) ALDH1A1MAPTLMNAPTGS2TDP1
Glycine SCHEMBL1694000 0.94 ALDH1A1 (0.41) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL6136334 0.93 ALDH1A1 (0.40) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL7568157 0.93 ALDH1A1 (0.40) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL619330 0.93 ALDH1A1 (0.40) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL8346127 0.93 ALDH1A1 (0.40) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL8745360 0.93 ALDH1A1 (0.40) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL15499 0.93 ALDH1A1 (0.40) ALDH1A1MAPTLMNAPTGS2TDP1
SCHEMBL2189880 0.87 CA12 (0.35) ALDH1A1MAPTLMNAPTGS2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5627268-A MAKING A DESIRED PEPTIDE IN TRANSGENIC ANIMALS DNX BIOTHERAPEUTICS (US) 1997-05-06 — — US claimed
EP-0457314-A1 Nutrient compositions containing peptides CLINTEC NUTRITION COMPANY (US) 1991-11-21 — — EP claimed
US-12600792-B2 Monoclonal antibodies and methods of use ELANCO TIERGESUNDHEIT AG (CH) 2026-04-14 — — US disclosed
EP-4530630-A2 MONOCLONAL ANTIBODIES AND METHODS OF USE Elanco Tiergesundheit AG (CH) 2025-04-02 — — EP disclosed
US-20240150452-A1 MULTIFUNCTIONAL PROTEIN MOLECULES COMPRISING DECORIN AND USE THEREOF CATALENT PHARMA SOLUTIONS, LLC 2024-05-09 — — US disclosed
US-11879009-B2 Multifunctional protein molecules comprising decorin and use thereof CATALENT PHARMA SOLUTIONS, LLC (US) 2024-01-23 — — US disclosed
US-20220275074-A1 MULTIFUNCTIONAL PROTEIN MOLECULES COMPRISING DECORIN AND USE THEREOF ARES CAPITAL CORPORATION, AS COLLATERAL AGENT 2022-09-01 — — US disclosed
US-20220251230-A1 MONOCLONAL ANTIBODIES AND METHODS OF USE ELANCO TIERGESUNDHEIT AG (CH) 2022-08-11 — — US disclosed
US-11377488-B2 Multifunctional protein molecules comprising decorin and use thereof CATALENT PHARMA SOLUTIONS, LLC (US) 2022-07-05 — — US disclosed
US-11319377-B2 Monoclonal antibodies and methods of use ELANCO TIERGESUNDHEIT AG (CH) 2022-05-03 — — US disclosed
US-20130337456-A1 COMPARATIVE SEQUENCE ANALYSIS PROCESSES AND SYSTEMS SEQUENOM, INC. (US) 2013-12-19 — — US disclosed
US-4803156-A DETECTION OF HEPATITIS B ANTIBODIES NEW YORK BLOOD CENTER (US) 1989-02-07 — — US disclosed
EP-0263933-A1 A cDNA coding for carcinoembryonic antigen MILES INC. (US) 1988-04-20 — — EP disclosed
CN-87102945-A Pre-S gene coded peptide hepatilis B immunogens, vaccine, diagnostic agent and synthetic lipid vesicle carriers — 1988-04-20 — — CN disclosed
CN-87103084-A The complex immunogen that contains synthetic peptide — 1988-02-03 — — CN disclosed
US-4716148-A POLYPEPTIDE HORMONE FROM MAMMALIAN THYMUS HOFFMAN-LA ROCHE INC. (US) 1987-12-29 — — US disclosed
EP-0244719-A2 Complex immunogen containing synthetic peptides New York Blood Center, Inc. (US) 1987-11-11 — — EP disclosed
EP-0243913-A2 Pre-s gene codes peptide hepatitis b immunogens, vaccines, diagnostics, and synthetic lipid vesicle carriers New York Blood Center, Inc. (US) 1987-11-04 — — EP disclosed
US-4659694-A POLYPEPTIDE HORMONE FOR PREVENTION OF INFECTIONS HOFFMANN-LA ROCHE INC. (US) 1987-04-21 — — US disclosed
EP-0154902-A2 Pre-S gene coded peptide hepatitis B immunogens, vaccines, diagnostics, and synthetic lipid vesicle carriers New York Blood Center, Inc. (US) 1985-09-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240150452-A1 MULTIFUNCTIONAL PROTEIN MOLECULES COMPRISING DECORIN AND USE THEREOF CD2BP2, DSTN, SDCBP ALDH1A1 3337/4885MAPT 3409/4885LMNA 2473/4885
US-11879009-B2 Multifunctional protein molecules comprising decorin and use thereof CD2BP2, DSTN, SDCBP ALDH1A1 3337/4885MAPT 3409/4885LMNA 2473/4885
US-12600792-B2 Monoclonal antibodies and methods of use IGSF11, IGLV6-57, CDY1; CDY1B ALDH1A1 3911/4885MAPT 2935/4885LMNA 4803/4885
US-11377488-B2 Multifunctional protein molecules comprising decorin and use thereof CD2BP2, DSTN, SDCBP ALDH1A1 3337/4885MAPT 3409/4885LMNA 2473/4885
US-20220275074-A1 MULTIFUNCTIONAL PROTEIN MOLECULES COMPRISING DECORIN AND USE THEREOF CD2BP2, DSTN, SDCBP ALDH1A1 3337/4885MAPT 3409/4885LMNA 2473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.