Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9789462 | 0.94 | ADRB2 (0.41) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| SCHEMBL3268573 | 0.94 | ADRB2 (0.45) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| Bromide SCHEMBL9410940 | 0.91 | ADRB2 (0.43) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| Fluoride SCHEMBL9410959 | 0.91 | ADRB2 (0.43) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| Hydrochloric Acid SCHEMBL1359753 | 0.91 | ADRB2 (0.43) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| Iodide SCHEMBL9410962 | 0.91 | ADRB2 (0.43) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| SCHEMBL6895599 | 0.88 | ADRB2 (0.41) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| SCHEMBL7188812 | 0.85 | THRB (0.41) | TSHRCA1CA2NR5A1THRB | |
| Acetone SCHEMBL27840890 | 0.81 | ALDH1A1 (0.52) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| SCHEMBL10501543 | 0.78 | ADRB2 (0.33) | ADRB2ADRB1ADRB3TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025056984-A1 | A NOVEL PROCESS FOR THE PREPARATION OF BEXAGLIFLOZIN A SGLT2 INHIBITOR AND ITS INTERMEDIATES THEREOF | VIJAYASRI ORGANICS PRIVATE LIMITED (IN) | 2025-03-20 | — | — | WO | claimed |
| WO-2025056984-A1 | A NOVEL PROCESS FOR THE PREPARATION OF BEXAGLIFLOZIN A SGLT2 INHIBITOR AND ITS INTERMEDIATES THEREOF | VIJAYASRI ORGANICS PRIVATE LIMITED (IN) | 2025-03-20 | — | — | WO | disclosed |
| US-20160280619-A1 | PROCESS FOR THE PREPARATION OF 4-BROMO-1-CHLORO-2-(4-ETHOXYBENZYL)BENZENE | RANBAXY LABORATORIES LIMITED (IN) | 2016-09-29 | — | — | US | disclosed |
| EP-3063116-A1 | PROCESS FOR THE PREPARATION OF 4-BROMO-1-CHLORO-2-(4-ETHOXYBENZYL)BENZENE | Sun Pharmaceutical Industries Ltd (IN) | 2016-09-07 | — | — | EP | disclosed |
| WO-2015063726-A1 | PROCESS FOR THE PREPARATION OF 4-BROMO-1-CHLORO-2-(4-ETHOXYBENZYL)BENZENE | RANBAXY LABORATORIES LIMITED (IN) | 2015-05-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160280619-A1 | PROCESS FOR THE PREPARATION OF 4-BROMO-1-CHLORO-2-(4-ETHOXYBENZYL)BENZENE | SLC5A2, SLC5A1, DPP4 | ADRB2 247/4885ADRB1 115/4885ADRB3 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.