Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2208538 | 1.00 | LMNA (0.50) | LMNATSHRCYP2D6CYP3A4SLC6A2 | |
| SCHEMBL19415540 | 0.84 | LMNA (0.39) | LMNATSHRCYP2D6CYP3A4SLC6A2 | |
| SCHEMBL5107133 | 0.84 | LMNA (0.61) | LMNATSHRCYP2D6PDE2ATRPA1 | |
| SCHEMBL5107136 | 0.84 | LMNA (0.61) | LMNATSHRCYP2D6PDE2ATRPA1 | |
| SCHEMBL30172716 | 0.84 | LMNA (0.61) | LMNATSHRCYP2D6PDE2ATRPA1 | |
| SCHEMBL5107130 | 0.84 | LMNA (0.61) | LMNATSHRCYP2D6PDE2ATRPA1 | |
| SCHEMBL6895253 | 0.82 | PPARG (0.43) | LMNATSHRCYP2D6CYP3A4SLC6A2 | |
| SCHEMBL11050837 | 0.80 | CYP2D6 (0.36) | LMNATSHRCYP2D6CYP3A4SLC6A2 | |
| SCHEMBL2850755 | 0.80 | CYP2D6 (0.36) | LMNATSHRCYP2D6CYP3A4SLC6A2 | |
| SCHEMBL10595562 | 0.80 | IDO1 (0.42) | LMNATSHRCYP2D6CYP3A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063281-A2 | PROCESS FOR THE CHIRAL RESOLUTION OF ACETATES TO (R)-ALCOHOLS EMPLOYING FUSARIUM PROLIFERATUM | Council of Scientific and Industrial Research (IN) | 2016-09-07 | — | — | EP | disclosed |
| WO-2015063796-A2 | A PROCESS OF CHIRAL RESOLUTION OF CYCLIC AND ACYCLIC ACETATES TO ENANTIOMERICALLY PURE (R)--ALCOHOLS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-05-07 | — | — | WO | disclosed |