Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8216569 | 0.86 | ALDH1A1 (0.46) | PPARGALDH1A1KDM4EPPARALMNA | |
| SCHEMBL30374198 | 0.84 | CSNK1E (0.40) | PPARGALDH1A1KDM4ECSNK1ECNR2 | |
| SCHEMBL30374958 | 0.84 | CSNK1E (0.40) | PPARGALDH1A1KDM4ECSNK1ECNR2 | |
| SCHEMBL15050733 | 0.84 | CSNK1E (0.40) | PPARGALDH1A1KDM4ECSNK1ECNR2 | |
| SCHEMBL15050136 | 0.84 | CSNK1E (0.40) | PPARGALDH1A1KDM4ECSNK1ECNR2 | |
| SCHEMBL15050140 | 0.84 | CSNK1E (0.40) | PPARGALDH1A1KDM4ECSNK1ECNR2 | |
| SCHEMBL15050734 | 0.84 | CSNK1E (0.40) | PPARGALDH1A1KDM4ECSNK1ECNR2 | |
| SCHEMBL15050139 | 0.84 | CSNK1E (0.40) | PPARGALDH1A1KDM4ECSNK1ECNR2 | |
| SCHEMBL27599791 | 0.82 | CYSLTR2 (0.42) | ALDH1A1KDM4ECNR2CYP3A4POLB | |
| SCHEMBL16685696 | 0.82 | LMNA (0.50) | LMNACYP3A4CYP2D6SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040146495-A1 | Method for assisting in differential diagnosis and treatment of autistic syndromes | REPLIGEN CORPORATION, A DELAWARE CORPORATION | 2004-07-29 | — | — | US | claimed |