Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15324177 | 0.78 | GRM5 (0.45) | GRM5CYP1A2PTGES2OGACHRNB2 | |
| SCHEMBL18810068 | 0.74 | GRM5 (0.41) | GRM5CYP1A2PTGES2OGAALDH1A1 | |
| SCHEMBL15991273 | 0.72 | ADRA2A (0.38) | GRM5ALDH1A1KDM4EMCHR1ADRA2A | |
| SCHEMBL8575385 | 0.72 | CHRNA7 (0.33) | MCHR1 | |
| SCHEMBL15322866 | 0.71 | MAPT (0.43) | GRM5CYP1A2ALDH1A1ADRA2AADRA2B | |
| SCHEMBL18478408 | 0.71 | CYP1A2 (0.41) | GRM5CYP1A2OGACHRNB2CHRNA2 | |
| SCHEMBL9855343 | 0.71 | CHRNB2 (0.38) | GRM5CYP1A2OGAALDH1A1CHRNB2 | |
| SCHEMBL9855339 | 0.71 | CHRNB2 (0.38) | GRM5CYP1A2OGAALDH1A1CHRNB2 | |
| SCHEMBL21258035 | 0.70 | FFAR1 (0.47) | GRM5CYP1A2 | |
| SCHEMBL9855115 | 0.69 | CHRNB2 (0.40) | GRM5CYP1A2OGACHRNB2CHRNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015066413-A1 | OXAZOLIDINONE HYDROXAMIC ACID COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | NOVARTIS AG (CH) | 2015-05-07 | — | — | WO | disclosed |