Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8575554 | 0.85 | SLC18A3 (0.33) | CHRNA7 | |
| SCHEMBL8921096 | 0.79 | ALDH1A1 (0.35) | CHRNA7 | |
| SCHEMBL8573706 | 0.73 | TTR (0.41) | CHRNA7 | |
| SCHEMBL16685697 | 0.72 | GRM5 (0.45) | MCHR1 | |
| SCHEMBL8574139 | 0.69 | CHRNA7 (0.50) | CHRNA7 | |
| Hydrochloric Acid SCHEMBL8578709 | 0.68 | CHRNA7 (0.49) | CHRNA7 | |
| SCHEMBL8572852 | 0.68 | ALDH1A1 (0.47) | CHRNA7 | |
| SCHEMBL8712010 | 0.66 | CYP1A1 (0.38) | — | |
| SCHEMBL8707234 | 0.65 | HRH3 (0.37) | — | |
| SCHEMBL8574500 | 0.65 | ACACB (0.39) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731323-A | Quinuclidine derivatives as squalene synthase inhibitors | ZENECA LIMITED (GB) | 1998-03-24 | — | — | US | disclosed |