Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 4/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12801761 | 0.89 | PARP14 (0.39) | PARP14PARP10PARP1ALDH1A1KDM4E | |
| SCHEMBL1668681 | 0.88 | MGLL (0.48) | PARP14PARP10ALDH1A1KDM4ELMNA | |
| SCHEMBL22634104 | 0.83 | PARP14 (0.42) | PARP14PARP10PARP1ALDH1A1KDM4E | |
| SCHEMBL13835308 | 0.82 | BCL9 (0.40) | PARP14PARP10PARP1ALDH1A1LMNA | |
| SCHEMBL1668846 | 0.81 | PARP14 (0.46) | PARP14PARP10ALDH1A1KDM4ELMNA | |
| SCHEMBL11903466 | 0.80 | PARP10 (0.43) | PARP14PARP10PARP1ALDH1A1KDM4E | |
| SCHEMBL14879836 | 0.79 | MGLL (0.51) | PARP14PARP10PARP1KMT2AEGLN1 | |
| SCHEMBL1668837 | 0.79 | MGLL (0.56) | — | |
| SCHEMBL1668732 | 0.77 | GAA (0.44) | PARP14PARP10ALDH1A1KDM4ELMNA | |
| SCHEMBL1668899 | 0.76 | EGLN1 (0.46) | PARP14PARP10EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2485678-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | Cornell University (US) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | disclosed |