Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.45 |
| ▸ | QDPR | P09417 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25321962 | 0.89 | ERN1 (0.44) | EGLN1MGLLHTR1AHTR1BHTR2A | |
| SCHEMBL19387560 | 0.88 | MGLL (0.46) | EGLN1MGLLCA12CA1CA2 | |
| SCHEMBL1668837 | 0.88 | MGLL (0.56) | MGLL | |
| SCHEMBL13976872 | 0.88 | MGLL (0.46) | MGLLCA12CA1CA2CA9 | |
| SCHEMBL13976871 | 0.88 | MGLL (0.46) | MGLLCA12CA1CA2CA9 | |
| SCHEMBL15985380 | 0.88 | QDPR (0.48) | MGLLCA12CA1CA2CA9 | |
| SCHEMBL14879836 | 0.86 | MGLL (0.51) | EGLN1MGLLPARP14PARP10 | |
| SCHEMBL15981376 | 0.85 | MGLL (0.46) | MGLLCA12CA1CA2CA9 | |
| SCHEMBL1668896 | 0.85 | CNR2 (0.44) | EGLN1MGLLTRPV6QDPR | |
| SCHEMBL12801511 | 0.84 | TPSAB1 (0.56) | CA12CA1CA2CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2485678-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | Cornell University (US) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | disclosed |