Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29761172 | 1.00 | CNR2 (0.36) | CNR2DPP4SHBGMEN1ALDH1A1 | |
| SCHEMBL5407267 | 1.00 | CNR2 (0.36) | CNR2DPP4SHBGMEN1ALDH1A1 | |
| SCHEMBL1668637 | 1.00 | CNR2 (0.36) | CNR2DPP4SHBGMEN1ALDH1A1 | |
| SCHEMBL30148076 | 1.00 | CNR2 (0.36) | CNR2DPP4SHBGMEN1ALDH1A1 | |
| SCHEMBL13320075 | 0.79 | CNR2 (0.35) | CNR2DPP4SHBG | |
| SCHEMBL24052391 | 0.77 | CNR2 (0.35) | CNR2DPP4SHBGMEN1ALDH1A1 | |
| SCHEMBL9360142 | 0.77 | CNR2 (0.35) | CNR2DPP4SHBG | |
| SCHEMBL253323 | 0.77 | CNR2 (0.35) | CNR2DPP4SHBG | |
| SCHEMBL7673902 | 0.77 | CNR2 (0.35) | CNR2DPP4SHBG | |
| SCHEMBL6507028 | 0.77 | CNR2 (0.35) | CNR2DPP4SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2485678-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | Cornell University (US) | 2012-08-15 | — | — | EP | claimed |
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | claimed |
| US-9771345-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2017-09-26 | — | — | US | disclosed |
| US-20140357806-A1 | THERMAL-RESPONSIVE POLYMER NETWORKS, COMPOSITIONS, AND METHODS AND APPLICATIONS RELATED THERETO | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL (US) | 2014-12-04 | — | — | US | disclosed |
| US-20140161729-A1 | COFLUORONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2014-06-12 | — | — | US | disclosed |
| US-8597630-B2 | Thermal-responsive polymer networks, compositions, and methods and applications related thereto | UNIVERSITY OF MASSACHUSETTS (US) | 2013-12-03 | — | — | US | disclosed |
| US-20120295874-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2012-11-22 | — | — | US | disclosed |
| WO-2012154213-A1 | COFLUORONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2012-11-15 | — | — | WO | disclosed |
| EP-2485678-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | Cornell University (US) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011120002-A1 | THERMAL-RESPONSIVE POLYMER NETWORKS, COMPOSITIONS, AND METHODS AND APPLICATIONS RELATED THERETO | UNIVERSITY OF MASSACHUSETTS (US) | 2011-09-29 | — | — | WO | disclosed |
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | disclosed |
| US-20100280561-A1 | Thermal-Responsive Polymer Networks, Compositions, And Methods And Applications Related Thereto | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295874-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | MYOF, FTH1, HCCS | CNR2 2399/4885DPP4 3310/4885SHBG 300/4885 |
| US-20140161729-A1 | COFLUORONS AND METHODS OF MAKING AND USING THEM | TNFSF11, CD14, TNFRSF1A | CNR2 1466/4885DPP4 3760/4885SHBG 1432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.