Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.32 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.32 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 3/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668229 | 0.82 | CNR1 (0.37) | HTR2CPIK3CAPRKAA2PRMT5KDM4E | |
| SCHEMBL1670840 | 0.81 | TEAD1 (0.38) | PIK3CAPRKAA2KDM4EALDH1A1PRKAB2 | |
| SCHEMBL1668675 | 0.79 | CNR1 (0.36) | HTR2CPIK3CAPRKAA2KDM4EALDH1A1 | |
| SCHEMBL1668410 | 0.77 | KDM4E (0.49) | PIK3CAPRKAA2KDM4EALDH1A1 | |
| SCHEMBL12198419 | 0.75 | ADRB2 (0.46) | KDM4EALDH1A1PDE2AADRB2BCHE | |
| SCHEMBL1671394 | 0.75 | EPHX2 (0.46) | PIK3CAPRKAA2KDM4EALDH1A1 | |
| SCHEMBL1668510 | 0.73 | HIF1A (0.38) | PIK3CAPRKAA2KDM4EALDH1A1ADRB2 | |
| SCHEMBL1668754 | 0.73 | EPHX2 (0.40) | PIK3CAPRKAA2KDM4EALDH1A1ADRB2 | |
| SCHEMBL1669073 | 0.72 | PPARD (0.39) | KDM4EALDH1A1 | |
| SCHEMBL1668262 | 0.72 | KDM4E (0.48) | PIK3CAPRKAA2KDM4EALDH1A1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486033-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2012-08-15 | — | — | EP | claimed |
| WO-2011044001-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-04-14 | — | — | WO | claimed |