SCHEMBL1668692

SCHEMBL1668692

OB(O)c1cccs1.OB(O)c1cncnc1

nearest known ligand 0.64

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
CA5A P35218 1/20 0.31
CA7 P43166 1/20 0.31
ENPP2 Q13822 1/20 0.31
CA14 Q9ULX7 1/20 0.31
CA5B Q9Y2D0 1/20 0.31
CYP2E1 P05181 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2A6 P11509 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2B6 P20813 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38298 0.80
SCHEMBL6274268 0.78
SCHEMBL9139 0.76
Water SCHEMBL2326354 0.73 HCAR2 (0.36) CA4CA6CA5ACA7ENPP2
Water SCHEMBL1662662 0.73 HCAR2 (0.36) CA4CA6CA5ACA7ENPP2
Ethylene Glycol SCHEMBL27657993 0.72 MEN1 (0.34)
Magnesium Chloride Anhydrous SCHEMBL20694921 0.72 TSHR (0.37)
SCHEMBL28449625 0.70 CA4 (0.38) CA4CA6CA5ACA7ENPP2
SCHEMBL25205631 0.69 SMN1; SMN2 (0.34) CYP2C9
SCHEMBL526171 0.67 CES2 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012154213-A1 COFLUORONS AND METHODS OF MAKING AND USING THEM CORNELL UNIVERSITY (US) 2012-11-15 WO disclosed
EP-2485678-A1 COFERONS AND METHODS OF MAKING AND USING THEM Cornell University (US) 2012-08-15 EP disclosed
WO-2011043817-A1 COFERONS AND METHODS OF MAKING AND USING THEM CORNELL UNIVERSITY (US) 2011-04-14 WO disclosed