Ethylene Glycol

Ethylene Glycol

SCHEMBL27657993

OB(O)c1cccs1.OCCO

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
POLB P06746 1/20 0.34
RAB9A P51151 1/20 0.34
KMT2A Q03164 1/20 0.34
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
DPP4 P27487 1/20 0.33
GSK3B P49841 1/20 0.32
MGLL Q99685 1/20 0.32
DAO P14920 1/20 0.32
TSHR P16473 1/20 0.32
CYP2C19 P33261 1/20 0.31
ADRA2A P08913 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
ATM Q13315 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38298 0.91
SCHEMBL6274268 0.88
Magnesium Chloride Anhydrous SCHEMBL20694921 0.82 TSHR (0.37) MEN1NPC1ALDH1A1LMNAPOLB
Cysteamine SCHEMBL27828964 0.79 TAAR1 (0.39) MEN1NPC1ALDH1A1LMNAPOLB
SCHEMBL30307578 0.79 NPC1 (0.34) MEN1NPC1ALDH1A1LMNAPOLB
SCHEMBL25205631 0.78 SMN1; SMN2 (0.34) NPC1ALDH1A1LMNARAB9ACES2
SCHEMBL526171 0.75 CES2 (0.39) MEN1NPC1ALDH1A1LMNAPOLB
SCHEMBL28449625 0.75 CA4 (0.38) MEN1ALDH1A1LMNAKMT2AMGLL
SCHEMBL1138357 0.74 ALDH1A1 (0.31) ALDH1A1
SCHEMBL1668692 0.72 CA4 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1972695-A Treatment or prevention of skin conditions or tissue conditions in animals using boryloxypyridylmethanones ANACOR PHARMACEUTICALS INC (US) 2007-05-30 CN disclosed
CN-1972694-A Antibiotics containing borinic acid complexes and methods of use ANACOR PHARMACEUTICALS INC (US) 2007-05-30 CN disclosed