SCHEMBL526171

SCHEMBL526171

OB(c1cccs1)c1cccs1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
DAO P14920 1/20 0.37
FBP1 P09467 1/20 0.36
ATM Q13315 1/20 0.36
NPC1 O15118 4/20 0.34
RAB9A P51151 4/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
POLB P06746 1/20 0.34
HDAC1 Q13547 1/20 0.34
PCSK9 Q8NBP7 1/20 0.33
ORAI1 Q96D31 1/20 0.33
ORAI2 Q96SN7 1/20 0.33
ORAI3 Q9BRQ5 1/20 0.33
TRPV6 Q9H1D0 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38298 0.83
SCHEMBL6274268 0.81
SCHEMBL1186594 0.79
SCHEMBL1477900 0.77 FBP1 (0.39) CES2CES1DAOFBP1ATM
Ethylene Glycol SCHEMBL27657993 0.75 MEN1 (0.34) CES2CES1DAOFBP1ATM
Magnesium Chloride Anhydrous SCHEMBL20694921 0.75 TSHR (0.37) CES2CES1DAOFBP1ATM
SCHEMBL12266209 0.74 LPL (0.50) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL13476017 0.74 ENPP2 (0.50) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL1187403 0.74 RAB9A (0.37) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL24426695 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583888-B2 Bi-specific extracellular matrix binding peptides and methods of use thereof UNIVERSITY OF TARTU (EE) 2026-03-24 US disclosed
US-20260048133-A1 METHODS AND COMPOSITIONS USING PEPTIDES AND PROTEINS WITH C-TERMINAL ELEMENTS SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INST (US) 2026-02-19 US disclosed
US-20250361270-A1 TARGETED DELIVERY SYSTEM AND METHODS OF USE THEREFOR SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INST (US) 2025-11-27 US disclosed
US-12290569-B2 Methods and compositions using peptides and proteins with c-terminal elements Sanford Burnham Prebys Medical Discovery Institute (US) 2025-05-06 US disclosed
US-12195558-B2 Targeted delivery system and methods of use therefor Sanford Burnham Prebys Medical Discovery Institute (US) 2025-01-14 US disclosed
US-20240391953-A1 TUMOR ASSOCIATED MONOCYTE/MACROPHAGE BINDING PEPTIDE AND METHODS OF USE THEREOF Sanford Burnham Prebys Medical Discovery Institute 2024-11-28 US disclosed
US-11981752-B2 Tumor associated monocyte/macrophage binding peptide and methods of use thereof Sanford Burnham Prebys Medical Discovery Institute (US) 2024-05-14 US disclosed
US-20240150397-A1 TARGETED DELIVERY SYSTEM AND METHODS OF USE THEREFOR Sanford Burnham Prebys Medical Discovery Institute 2024-05-09 US disclosed
US-11512110-B2 Targeted delivery system and methods of use therefor Sanford Burnham Prebys Medical Discovery Institute (US) 2022-11-29 US disclosed
US-20220175941-A1 METHODS AND COMPOSITIONS USING PEPTIDES AND PROTEINS WITH C-TERMINAL ELEMENTS SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE 2022-06-09 US disclosed
US-20080293675-A1 ANTIBIOTICS CONTAINING BORINIC ACID COMPLEXES AND METHODS OF USE ANACOR PHARMACEUTCALS INC. (US) 2008-11-27 US disclosed
US-7390806-B2 Antibiotics containing borinic acid complexes and methods of use ANACOR PHARMACEUTICALS, INC. (US) 2008-06-24 US disclosed
EP-1765359-A2 ANTIBIOTICS CONTAINING BORINIC ACID COMPLEXES AND METHODS OF USE Anacor Pharmaceuticals, Inc. (US) 2007-03-28 EP disclosed
EP-1638578-A2 HYDROLYTICALLY-RESISTANT BORON-CONTAINING THERAPEUTICS AND METHODS OF USE Anacor Pharmaceuticals, Inc. (US) 2006-03-29 EP disclosed
WO-2006007384-A2 ANTIBIOTICS CONTAINING BORINIC ACID COMPLEXES AND METHODS OF USE ANACOR PHARMACEUTICALS, INC. (US) 2006-01-19 WO disclosed
WO-2005013892-A9 HYDROLYTICALLY-RESISTANT BORON-CONTAINING THERAPEUTICS AND METHODS OF USE ANACOR PHARMACEUTICALS INC (US) 2005-04-14 WO disclosed
US-20050070503-A1 Antibiotics containing borinic acid complexes and methods of use ANACOR PHARMACEUTICALS, INC. 2005-03-31 US disclosed
US-20050054644-A1 Hydrolytically-resistant boron-containing therapeutics and methods of use ANACOR PHARMACEUTICALS, LLC 2005-03-10 US disclosed
WO-2005013892-A2 HYDROLYTICALLY-RESISTANT BORON-CONTAINING THERAPEUTICS AND METHODS OF USE ANACOR PHARMACEUTICALS, INC. (US) 2005-02-17 WO disclosed
WO-1997011951-A1 FUNGICIDES ZENECA LIMITED (GB) 1997-04-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260048133-A1 METHODS AND COMPOSITIONS USING PEPTIDES AND PROTEINS WITH C-TERMINAL ELEMENTS CMKLR2, CRKL, CMKLR1 CES2 2967/4885CES1 3746/4885DAO 3921/4885
US-20050070503-A1 Antibiotics containing borinic acid complexes and methods of use BPGM, BROX, TBCA CES2 4008/4885CES1 4327/4885DAO 196/4885
US-12583888-B2 Bi-specific extracellular matrix binding peptides and methods of use thereof FN1, EDNRB, TNFSF11 CES2 4831/4885CES1 4590/4885DAO 3328/4885
US-20050054644-A1 Hydrolytically-resistant boron-containing therapeutics and methods of use BTD, GAA, GBA3 CES2 123/4885CES1 256/4885DAO 251/4885
US-20080293675-A1 ANTIBIOTICS CONTAINING BORINIC ACID COMPLEXES AND METHODS OF USE BPGM, BROX, TBCA CES2 4008/4885CES1 4327/4885DAO 196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.