Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SUV39H2 | Q9H5I1 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16685207 | 0.82 | KDM4E (0.41) | KDM4EPOLBMAPTSMN1; SMN2TDP1 | |
| SCHEMBL16687074 | 0.81 | KDM4E (0.44) | KDM4EPOLBMAPTSMN1; SMN2TDP1 | |
| SCHEMBL4031415 | 0.80 | ALDH1A1 (0.53) | KDM4EPOLBMAPTSMN1; SMN2PKM | |
| SCHEMBL16691126 | 0.79 | KDM4E (0.76) | KDM4EPOLBTLR9TLR7MAPT | |
| SCHEMBL15418923 | 0.71 | KDM4E (0.39) | KDM4EPOLBMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL15418875 | 0.71 | PIK3CA (0.42) | KDM4EPOLBMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL16686872 | 0.70 | RAB9A (0.50) | KDM4EPOLBMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL15419068 | 0.70 | RAB9A (0.42) | KDM4EPOLBMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL18026511 | 0.68 | TLR9 (0.49) | KDM4EPOLBTLR9TLR7MAPT | |
| SCHEMBL2440400 | 0.68 | NR4A2 (0.53) | KDM4EPOLBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063150-B1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | Bayer Pharma AG (DE) | 2017-11-22 | — | — | EP | disclosed |
| EP-3063150-A1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | Bayer Pharma Aktiengesellschaft (DE) | 2016-09-07 | — | — | EP | disclosed |
| WO-2015063093-A1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-05-07 | — | — | WO | disclosed |