Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16686972 | 0.82 | KDM4E (0.48) | KDM4EPOLBCYP1A2LMNACYP3A4 | |
| SCHEMBL7982712 | 0.81 | BCL9 (0.34) | KDM4EPOLBRAB9ALMNAPIK3CA | |
| SCHEMBL15418923 | 0.81 | KDM4E (0.39) | KDM4EPOLBRAB9ACYP1A2GAA | |
| SCHEMBL15418875 | 0.80 | PIK3CA (0.42) | KDM4EPOLBRAB9ALMNAPIK3CA | |
| SCHEMBL16686872 | 0.80 | RAB9A (0.50) | KDM4EPOLBRAB9ACYP1A2LMNA | |
| SCHEMBL4031415 | 0.80 | ALDH1A1 (0.53) | KDM4EPOLBRAB9ACYP1A2CYP3A4 | |
| SCHEMBL15419068 | 0.79 | RAB9A (0.42) | KDM4EPOLBRAB9APIK3CAGAA | |
| SCHEMBL15418816 | 0.79 | MAP3K5 (0.48) | KDM4EPOLBRAB9ALMNAPIK3CA | |
| SCHEMBL3545619 | 0.79 | KDM4E (0.64) | KDM4EPOLBRAB9ACYP1A2LMNA | |
| SCHEMBL15418922 | 0.77 | PIK3CA (0.39) | KDM4EPOLBRAB9ALMNAPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063150-B1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | Bayer Pharma AG (DE) | 2017-11-22 | — | — | EP | disclosed |
| EP-3063150-A1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | Bayer Pharma Aktiengesellschaft (DE) | 2016-09-07 | — | — | EP | disclosed |
| WO-2015063093-A1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-05-07 | — | — | WO | disclosed |