Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9725520 | 0.97 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL495967 | 0.97 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL820368 | 0.97 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL4916495 | 0.97 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL18429967 | 0.97 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL9177542 | 0.93 | TSHR (0.53) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL167089 | 0.93 | TSHR (0.50) | TSHRTHRBCES2CES1DNM1 | |
| Lithium Ion SCHEMBL15135032 | 0.90 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL344563 | 0.90 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 | |
| Lithium Ion SCHEMBL938657 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101035818-B | Ziegler-natta catalyst, method for the production thereof and use thereof for the polymerization of olefins | NOVOLEN TECH HOLDINGS CV | 2011-08-17 | — | — | CN | claimed |
| US-7329626-B2 | Ziegler-Natta catalyst, preparation, and use for the polymerization of alkenes | LUMMUS NOVOLEN TECHNOLOGY GMBH (NL) | 2008-02-12 | — | — | US | claimed |
| CN-101035818-A | Ziegler-natta catalyst, method for the production thereof and use thereof for the polymerization of olefins | NOVOLEN TECH HOLDINGS CV (NL) | 2007-09-12 | — | — | CN | claimed |
| EP-1805230-A1 | ZIEGLER-NATTA CATALYST, PREPARATION, AND USE FOR THE POLYMERIZATION OF ALKENES | Novolen Technology Holdings, C.V. (NL) | 2007-07-11 | — | — | EP | claimed |
| US-7232785-B2 | Solid catalytic component and catalytic system of the ziegler-natta type, process for their preparation and their use in the polymerization of alk-1-enes | ABB LUMMUS GLOBAL, INC. (US) | 2007-06-19 | — | — | US | claimed |
| WO-2006028736-A1 | ZIEGLER-NATTA CATALYST, PREPARATION, AND USE FOR THE POLYMERIZATION OF ALKENES | NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) | 2006-03-16 | — | — | WO | claimed |
| US-20060052237-A1 | Ziegler-Natta catalyst, preparation, and use for the polymerization of alkenes | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2006-03-09 | — | — | US | claimed |
| US-20250376547-A1 | CONTINUOUS OLEFIN POLYMERIZATION PROCESS IN THE PRESENCE OF AN ANTISTATIC AGENT | BASELL POLYOLEFINE GMBH (DE) | 2025-12-11 | — | — | US | disclosed |
| EP-4551615-B1 | CONTINUOUS OLEFIN POLYMERIZATION PROCESS IN THE PRESENCE OF AN ANTISTATIC AGENT | BASELL POLYOLEFINE GMBH (DE) | 2025-12-03 | — | — | EP | disclosed |
| EP-3902849-B1 | PROCESS FOR PREPARATION OF POLYETHYLENE | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2025-10-01 | — | — | EP | disclosed |
| US-12240963-B2 | Process for preparation of polyethylene | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2025-03-04 | — | — | US | disclosed |
| US-12103988-B2 | Gas-phase process for preparing ethylene polymers | BASELL POLYOLEFINE GMBH (DE) | 2024-10-01 | — | — | US | disclosed |
| US-12091475-B2 | Process for preparation of multimodal polyolefin | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2024-09-17 | — | — | US | disclosed |
| EP-1120158-A1 | Catalytic systems of the Ziegler-Natta type | Basell Polypropylen GmbH (DE) | 2001-08-01 | — | — | EP | disclosed |
| US-6221984-B1 | Random propylene copolymer | BASF AKTIENGESELLSCHAFT (DE) | 2001-04-24 | — | — | US | disclosed |
| EP-0969044-A1 | Polymer blends | TARGOR GmbH (DE) | 2000-01-05 | — | — | EP | disclosed |
| EP-0945472-A2 | Statistic propylene copolymers | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-29 | — | — | EP | disclosed |
| EP-0887357-A1 | Propylene polymers | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-30 | — | — | EP | disclosed |
| EP-0881239-A1 | Statistic propylene copolymers | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-02 | — | — | EP | disclosed |
| EP-0864591-A1 | High crystalline propylene homopolymers | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-16 | — | — | EP | disclosed |