Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18429967 | 1.00 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL4916495 | 1.00 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL495967 | 1.00 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL820368 | 1.00 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL166873 | 0.97 | TSHR (0.53) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL9177542 | 0.97 | TSHR (0.53) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL167089 | 0.96 | TSHR (0.50) | TSHRTHRBCES2CES1DNM1 | |
| Lithium Ion SCHEMBL939261 | 0.93 | — | — | |
| SCHEMBL344563 | 0.93 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL5074438 | 0.93 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118027257-A | Olefin polymerization catalyst, application thereof and preparation method of polypropylene | 万华化学集团股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-117924571-A | Process for preparing heterophasic propylene copolymers | 北欧化工股份公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-110603270-B | Propylene-ethylene random copolymer with improved radiation resistance | 博里利斯股份公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-113924211-A | Multilayer polypropylene film | 北欧化工公司 | 2022-01-11 | — | — | CN | disclosed |
| CN-110072897-B | Polypropylene composition with low seal initiation temperature and high melting temperature | 博里利斯股份公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-113330042-A | Random propylene polymer composition and its use in extrusion blow moulding | 北欧化工股份公司 | 2021-08-31 | — | — | CN | disclosed |
| CN-111051423-B | Polypropylene composition | 博里利斯股份公司 | 2021-07-20 | — | — | CN | disclosed |
| CN-113015753-A | Catalyst and preparation method thereof | 北欧化工公司 | 2021-06-22 | — | — | CN | disclosed |
| CN-112566976-A | Polypropylene composition with improved coatability | 北欧化工公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-112566975-A | Polypropylene composition with improved coatability | 北欧化工公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-110062776-B | Polypropylene composition with low seal initiation temperature and high melting temperature | 博里利斯股份公司 | 2020-07-14 | — | — | CN | disclosed |
| CN-111356736-A | Fiber reinforced polypropylene composition | 北欧化工公司 | 2020-06-30 | — | — | CN | disclosed |
| CN-111065678-A | Polypropylene composition | 北欧化工公司 | 2020-04-24 | — | — | CN | disclosed |
| CN-111051423-A | Polypropylene composition | 博里利斯股份公司 | 2020-04-21 | — | — | CN | disclosed |
| CN-111032773-A | Polypropylene composition | 北欧化工公司 | 2020-04-17 | — | — | CN | disclosed |
| CN-109476892-B | Fiber reinforced polypropylene composite | 博里利斯股份公司 | 2020-03-27 | — | — | CN | disclosed |
| CN-110603270-A | Propylene-ethylene random copolymer with improved radiation resistance | 博里利斯股份公司 | 2019-12-20 | — | — | CN | disclosed |
| US-5153031-A | Use of hydrogen peroxide in preparing magnesium containing silicate sols for coating and fiber formation | CORNELL RESEARCH FOUNDATION, INC. (US) | 1992-10-06 | — | — | US | disclosed |
| US-5019293-A | Use of hydrogen peroxide in preparing magnesium containing silicate sols for coating and fiber formation | CORNELL RESEARCH FOUNDATION, INC. (US) | 1991-05-28 | — | — | US | disclosed |
| WO-1991000140-A1 | USE OF HYDROGEN PEROXIDE IN PREPARING MAGNESIUM CONTAINING SILICATE SOLS FOR COATING AND FIBER FORMATION | CORNELL RESEARCH FOUNDATION, INC. (US) | 1991-01-10 | — | — | WO | disclosed |