Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18429967 | 1.00 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL4916495 | 1.00 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL9725520 | 1.00 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL820368 | 1.00 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL166873 | 0.97 | TSHR (0.53) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL9177542 | 0.97 | TSHR (0.53) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL167089 | 0.96 | TSHR (0.50) | TSHRTHRBCES2CES1DNM1 | |
| Lithium Ion SCHEMBL939261 | 0.93 | — | — | |
| SCHEMBL344563 | 0.93 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL5074438 | 0.93 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119841984-A | Catalyst component for ethylene polymerization reaction, preparation method and application | 中国石油化工股份有限公司 | 2025-04-18 | — | — | CN | claimed |
| CN-117964815-A | Catalyst component for ethylene polymerization reaction, preparation method and application | 中国石油化工股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117964816-A | Catalyst component and catalyst for ethylene polymerization, and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117659234-A | Magnesium alkoxide loaded olefin polymerization catalyst component, olefin polymerization catalyst containing same and application of catalyst | 中国石油天然气股份有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-116239804-A | Long-chain branched high-density polyethylene and preparation method thereof | 中国石油天然气股份有限公司 | 2023-06-09 | — | — | CN | claimed |
| CN-116082566-A | Preparation method of bimodal polyethylene resin and obtained bimodal polyethylene resin and tubular product | 中国石油化工股份有限公司 | 2023-05-09 | — | — | CN | claimed |
| CN-112759685-B | Catalyst component for ethylene polymerization reaction, preparation method thereof, catalyst and application thereof | 中国石油化工股份有限公司 | 2023-02-28 | — | — | CN | claimed |
| CN-112724301-B | Polyethylene resin, preparation method thereof and injection blow molding hollow product thereof | 中国石油化工股份有限公司 | 2022-11-18 | — | — | CN | claimed |
| CN-112745408-B | Bimodal polyethylene resin for extrusion blow molding of small hollow articles, preparation method and application thereof | 中国石油化工股份有限公司 | 2022-10-21 | — | — | CN | claimed |
| CN-109694424-B | Catalyst component for ethylene polymerization, preparation method thereof and catalyst for ethylene polymerization | 中国石油化工股份有限公司 | 2021-08-03 | — | — | CN | claimed |
| CN-109694423-B | Catalyst component for ethylene polymerization, preparation method thereof and catalyst for ethylene polymerization | 中国石油化工股份有限公司 | 2021-07-30 | — | — | CN | claimed |
| CN-108341902-B | Catalyst component for ethylene polymerization, preparation method thereof and catalyst for ethylene polymerization | 中国石油化工股份有限公司 | 2021-07-02 | — | — | CN | claimed |
| CN-112851892-A | Preparation method of polypropylene with high melt strength | 中国石油天然气股份有限公司 | 2021-05-28 | — | — | CN | claimed |
| CN-108341900-B | Catalyst component for ethylene polymerization, preparation method thereof and catalyst for ethylene polymerization | 中国石油化工股份有限公司 | 2021-05-11 | — | — | CN | claimed |
| CN-112759685-A | Catalyst component for ethylene polymerization reaction, preparation method thereof, catalyst and application thereof | 中国石油化工股份有限公司 | 2021-05-07 | — | — | CN | claimed |
| CN-112745408-A | Bimodal polyethylene resin for extrusion blow molding of small hollow articles, preparation method and application thereof | 中国石油化工股份有限公司 | 2021-05-04 | — | — | CN | claimed |
| CN-112724301-A | Polyethylene resin, preparation method thereof and injection blow molding hollow product thereof | 中国石油化工股份有限公司 | 2021-04-30 | — | — | CN | claimed |
| CN-107840911-B | Catalyst component for ethylene polymerization reaction, preparation method thereof, catalyst and application thereof | 中国石油化工股份有限公司 | 2020-09-15 | — | — | CN | claimed |
| CN-107840910-B | Catalyst component for ethylene polymerization reaction, preparation method thereof, catalyst and application thereof | 中国石油化工股份有限公司 | 2020-06-09 | — | — | CN | claimed |
| EP-1276776-B1 | CATALYST FOR PRODUCING AN ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE AND METHOD FOR PRODUCING AN ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE USING THE SAME | SAMSUNG GENERAL CHEMICALS CO (KR) | 2006-11-02 | — | — | EP | claimed |