Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18429967 | 1.00 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL495967 | 1.00 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL9725520 | 1.00 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL820368 | 1.00 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL166873 | 0.97 | TSHR (0.53) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL9177542 | 0.97 | TSHR (0.53) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL167089 | 0.96 | TSHR (0.50) | TSHRTHRBCES2CES1DNM1 | |
| Lithium Ion SCHEMBL939261 | 0.93 | — | — | |
| SCHEMBL344563 | 0.93 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL5074438 | 0.93 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3619219-B1 | LOW-VISCOSITY SOLUTIONS OF ALKALINE-EARTH METAL ALKOXIDES IN APROTIC SOLVENTS, METHOD FOR THE PRODUCTION OF SAME AND USE FOR THE PRODUCTION OF ZIEGLER-NATTA CATALYSTS | ALBEMARLE GERMANY GMBH (DE) | 2023-11-01 | — | — | EP | disclosed |
| EP-1541540-B1 | Process for the preparation of pure magnesium alkoxides | EVONIK DEGUSSA GMBH (DE) | 2008-04-02 | — | — | EP | disclosed |
| US-20080071119-A1 | Process for preparing alkoxy-pure alkaline-earth alkoxides | DEGUSSA AG (DE) | 2008-03-20 | — | — | US | disclosed |
| CN-1651375-A | Process for preparing alkoxy-pure alkaline-earth alkoxides | DEGUSSA (DE) | 2005-08-10 | — | — | CN | disclosed |
| US-20050159630-A1 | Process for preparing alkoxy-pure alkaline-earth alkoxides | DEGUSSA AG (DE) | 2005-07-21 | — | — | US | disclosed |
| EP-1541540-A1 | Process for the preparation of pure alkaline earth alkoxides | Degussa AG (DE) | 2005-06-15 | — | — | EP | disclosed |