Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16688220 | 0.95 | PKM (0.38) | PKMKDM4EPTGDR2CA1CA2 | |
| SCHEMBL18082523 | 0.91 | PTGDR2 (0.38) | PKMKDM4EPTGDR2CA1CA2 | |
| SCHEMBL16688200 | 0.90 | KDM4E (0.36) | PKMKDM4EPTGDR2CA1CA2 | |
| SCHEMBL16688169 | 0.88 | KDM4E (0.34) | PKMKDM4EPTGDR2CA1CA2 | |
| SCHEMBL18082518 | 0.87 | PTGDR2 (0.35) | PKMKDM4EPTGDR2CA1CA2 | |
| SCHEMBL16688210 | 0.87 | PTGDR2 (0.35) | PKMKDM4EPTGDR2CA1CA2 | |
| SCHEMBL16688175 | 0.87 | HRH4 (0.38) | KDM4ECA1CA2RECQL | |
| SCHEMBL16688193 | 0.86 | PTGDR2 (0.35) | PKMKDM4EPTGDR2CA1CA2 | |
| SCHEMBL16689438 | 0.85 | PKM (0.35) | PKMCA1CA2RECQLMAPT | |
| SCHEMBL16688152 | 0.85 | PTGDR2 (0.36) | KDM4EPTGDR2CA1CA2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447084-B2 | Antiparisitic and pesticidal isoxazoline compounds | MERIAL, INC. (US) | 2016-09-20 | — | — | US | disclosed |
| US-20150126523-A1 | ANTIPARISITIC AND PESTICIDAL ISOXAZOLINE COMPOUNDS | MERIAL LIMITED (US) | 2015-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150126523-A1 | ANTIPARISITIC AND PESTICIDAL ISOXAZOLINE COMPOUNDS | ACHE, PRDX1, CHRM1 | PKM 1835/4885KDM4E 2875/4885PTGDR2 634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.