Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16688190 | 0.92 | PTGDR2 (0.34) | PTGDR2KDM4EMAPT | |
| SCHEMBL16688153 | 0.92 | PTGDR2 (0.36) | PTGDR2KDM4EMAPT | |
| SCHEMBL16688150 | 0.91 | PTGDR2 (0.33) | PTGDR2KDM4E | |
| SCHEMBL18082514 | 0.91 | PTGDR2 (0.34) | PTGDR2KDM4EMAPT | |
| SCHEMBL18082512 | 0.89 | PTGDR2 (0.34) | PTGDR2KDM4EMAPT | |
| SCHEMBL16688158 | 0.88 | PTGDR2 (0.35) | PTGDR2KDM4EMAPT | |
| SCHEMBL16688193 | 0.86 | PTGDR2 (0.35) | PTGDR2KDM4EMAPT | |
| SCHEMBL16688228 | 0.86 | PTGDR2 (0.32) | PTGDR2KDM4EORAI1MAPT | |
| SCHEMBL16688173 | 0.86 | P2RX7 (0.34) | PTGDR2KDM4EMAPT | |
| SCHEMBL16688152 | 0.86 | PTGDR2 (0.36) | PTGDR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447084-B2 | Antiparisitic and pesticidal isoxazoline compounds | MERIAL, INC. (US) | 2016-09-20 | — | — | US | disclosed |
| US-20150126523-A1 | ANTIPARISITIC AND PESTICIDAL ISOXAZOLINE COMPOUNDS | MERIAL LIMITED (US) | 2015-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150126523-A1 | ANTIPARISITIC AND PESTICIDAL ISOXAZOLINE COMPOUNDS | ACHE, PRDX1, CHRM1 | PTGDR2 634/4885SLC5A2 1744/4885KDM4E 2875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.