⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13976328 | 1.00 | — | — | |
| SCHEMBL48327 | 0.68 | LMNA (0.36) | — | |
| SCHEMBL246149 | 0.63 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL13618063 | 0.62 | — | — | |
| SCHEMBL11291716 | 0.60 | — | — | |
| SCHEMBL3738807 | 0.60 | — | — | |
| SCHEMBL2790791 | 0.60 | — | — | |
| SCHEMBL18878029 | 0.60 | — | — | |
| SCHEMBL9800280 | 0.60 | AR (0.30) | — | |
| SCHEMBL23793961 | 0.59 | POLB (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2485678-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | Cornell University (US) | 2012-08-15 | — | — | EP | claimed |
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | claimed |