SCHEMBL48327

SCHEMBL48327

CC1(O)CNC(=O)NC1=O

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
TDP2 O95551 1/20 0.35
MAPT P10636 1/20 0.35
SMAD3 P84022 1/20 0.35
HSD17B10 Q99714 1/20 0.35
KDM4C Q9H3R0 1/20 0.35
MMP2 P08253 2/20 0.32
MMP9 P14780 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CRBN Q96SW2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6221243 0.75 SMN1; SMN2 (0.34) LMNAMMP2MMP9SMN1; SMN2CRBN
SCHEMBL12189561 0.75 CRBN (0.33) CRBN
SCHEMBL29138678 0.71 CRBN (0.31) CRBN
SCHEMBL29110862 0.71 CRBN (0.31) CRBN
SCHEMBL2473210 0.71 SMN1; SMN2 (0.32) LMNAMMP2MMP9SMN1; SMN2CRBN
SCHEMBL28864845 0.71 SMN1; SMN2 (0.32) LMNAMMP2MMP9SMN1; SMN2CRBN
SCHEMBL1583554 0.71 SMN1; SMN2 (0.32) LMNAMMP2MMP9SMN1; SMN2CRBN
SCHEMBL8769135 0.70 ALDH1A1 (0.43) LMNAMMP2MMP9
SCHEMBL24227250 0.70 SMN1; SMN2 (0.31) LMNASMN1; SMN2CRBN
SCHEMBL1668947 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180258474-A1 METHODS FOR DETERMINING BASE LOCATIONS IN A POLYNUCLEOTIDE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2018-09-13 US claimed
EP-3280793-A1 METHODS FOR DETERMINING BASE LOCATIONS IN A POLYNUCLEOTIDE The Regents of the University of California (US) 2018-02-14 EP claimed
WO-2016164363-A1 METHODS FOR DETERMING BASE LOCATIONS IN A POLYNUCLEOTIDE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-10-13 WO claimed
EP-1419247-B1 METHOD FOR THE PRODUCTION OF NUCLEIC ACIDS CONSISTING OF STOCHASTICALLY COMBINED PARTS OF SOURCE NUCLEIC ACIDS DIREVO BIOTECH AG (DE) 2006-09-20 EP claimed
EP-1579015-A4 METHOD FOR PCR CLEANUP AND OLIGONUCLEOTIDE REMOVAL APPLERA CORP (US) 2006-06-21 EP claimed
EP-1579015-A2 METHOD FOR PCR CLEANUP AND OLIGONUCLEOTIDE REMOVAL Applera Corporation (US) 2005-09-28 EP claimed
EP-1579015-A3 METHOD FOR PCR CLEANUP AND OLIGONUCLEOTIDE REMOVAL Applera Corporation (US) 2005-08-25 EP claimed
US-20050130142-A1 Method for the production of nucleic acids consisting of stochastically combined parts of source nucleic acids DIREVO BIOTECH AG (DE) 2005-06-16 US claimed
EP-1419247-A2 METHOD FOR THE PRODUCTION OF NUCLEIC ACIDS CONSISTING OF STOCHASTICALLY COMBINED PARTS OF SOURCE NUCLEIC ACIDS Direvo Biotech AG (DE) 2004-05-19 EP claimed
US-20040023220-A1 Integrated method for PCR cleanup and oligonucleotide removal APPLIED BIOSYSTEMS, LLC 2004-02-05 US claimed
WO-2004009851-A2 METHOD FOR PCR CLEANUP AND OLIGONUCLEOTIDE REMOVAL APPLERA CORPORATION (US) 2004-01-29 WO claimed
WO-2003012100-A2 METHOD FOR THE PRODUCTION OF NUCLEIC ACIDS CONSISTING OF STOCHASTICALLY COMBINED PARTS OF SOURCE NUCLEIC ACIDS DIREVO BIOTECH AG (DE) 2003-02-13 WO claimed
EP-1281757-A1 Method for the production of nucleic acids consisting of stochastically combined parts of source nucleic acids Direvo Biotech AG (DE) 2003-02-05 EP claimed
EP-0719265-A1 NUCLEOSIDE DERIVATIVES, METHODS FOR THE MANUFACTURE THEREOF AND SPECIFIC POLYCLONAL AND MONOCLONAL ANTIBODIES OF SAID DERIVATIVES COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1996-07-03 EP claimed
WO-1995007907-A1 NUCLEOSIDE DERIVATIVES, METHODS FOR THE MANUFACTURE THEREOF AND SPECIFIC POLYCLONAL AND MONOCLONAL ANTIBODIES OF SAID DERIVATIVES COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1995-03-23 WO claimed
EP-4735621-A1 NUCLEIC ACID SYNTHESIS ON REUSABLE SUPPORT DNA Script (FR) 2026-05-06 EP disclosed
EP-4665866-A1 REAGENTS AND METHODS FOR NORMALIZATION Twist Bioscience Corporation (US) 2025-12-24 EP disclosed
US-5561225-A Polynucleotide analogs containing sulfonate and sulfonamide internucleoside linkages SOUTHERN RESEARCH INSTITUTE (US) 1996-10-01 US disclosed
EP-0719265-A1 NUCLEOSIDE DERIVATIVES, METHODS FOR THE MANUFACTURE THEREOF AND SPECIFIC POLYCLONAL AND MONOCLONAL ANTIBODIES OF SAID DERIVATIVES COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1996-07-03 EP disclosed
WO-1995007907-A1 NUCLEOSIDE DERIVATIVES, METHODS FOR THE MANUFACTURE THEREOF AND SPECIFIC POLYCLONAL AND MONOCLONAL ANTIBODIES OF SAID DERIVATIVES COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1995-03-23 WO disclosed