Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.58 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 6/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.44 |
| ▸ | PRKCG | P05129 | 2/20 | 0.44 |
| ▸ | PRKCB | P05771 | 2/20 | 0.44 |
| ▸ | PRKCA | P17252 | 2/20 | 0.44 |
| ▸ | PRKCH | P24723 | 2/20 | 0.44 |
| ▸ | PRKCI | P41743 | 2/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.44 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL413367 | 1.00 | ALDH1A1 (0.62) | ALDH1A1EPHX1SPHK1SPHK2PRKD3 | |
| SCHEMBL16995925 | 1.00 | ALDH1A1 (0.62) | ALDH1A1EPHX1SPHK1SPHK2PRKD3 | |
| SCHEMBL28757032 | 1.00 | ALDH1A1 (0.62) | ALDH1A1EPHX1SPHK1SPHK2PRKD3 | |
| SCHEMBL873108 | 1.00 | ALDH1A1 (0.62) | ALDH1A1EPHX1SPHK1SPHK2PRKD3 | |
| SCHEMBL2102930 | 1.00 | ALDH1A1 (0.62) | ALDH1A1EPHX1SPHK1SPHK2PRKD3 | |
| SCHEMBL10514828 | 1.00 | ALDH1A1 (0.62) | ALDH1A1EPHX1SPHK1SPHK2PRKD3 | |
| SCHEMBL136872 | 1.00 | ALDH1A1 (0.62) | ALDH1A1EPHX1SPHK1SPHK2PRKD3 | |
| SCHEMBL14779258 | 1.00 | ALDH1A1 (0.62) | ALDH1A1EPHX1SPHK1SPHK2PRKD3 | |
| SCHEMBL15560286 | 1.00 | ALDH1A1 (0.62) | ALDH1A1EPHX1SPHK1SPHK2PRKD3 | |
| SCHEMBL27821359 | 1.00 | ALDH1A1 (0.62) | ALDH1A1EPHX1SPHK1SPHK2PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000048570-A1 | PHARMACEUTICAL COMPOSITION FOR BALANIC TRANSMUCOSAL ADMINISTRATION OF ALFUZOSIN | SANOFI-SYNTHELABO (FR) | 2000-08-24 | — | — | WO | claimed |
| EP-0728462-A2 | Cosmetic method and composition for treating hair loss | MacroChem Corporation (US) | 1996-08-28 | — | — | EP | claimed |
| US-20250195409-A1 | METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES | Ananda Scientific, Inc. (US) | 2025-06-19 | — | — | US | disclosed |
| US-20210330667-A1 | TOPICAL COMPOSITION OF NALBUPHINE AND METHOD FOR TREATING PRURITUS CONDITION, PAIN, OR INFLAMMATORY CONDITION BY USING THE SAME | LUMOSA THERAPEUTICS CO., LTD. (TW) | 2021-10-28 | — | — | US | disclosed |
| WO-2015051525-A1 | SYNTHESIS OF ACETAL/KETAL | RHODIA OPERATIONS (FR) | 2015-04-16 | — | — | WO | disclosed |
| US-8916329-B2 | Hardmask composition and associated methods | CHEIL INDUSTRIES, INC. (KR) | 2014-12-23 | — | — | US | disclosed |
| EP-2303265-B1 | STABLE TOPICAL FORMULATION COMPRISING VORICONAZOLE | GLENMARK PHARMACEUTICALS LTD (IN) | 2014-12-10 | — | — | EP | disclosed |
| US-20110105448-A1 | Stable Topical Formulation Comprising Voriconazole | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2011-05-05 | — | — | US | disclosed |
| EP-2303265-A2 | STABLE TOPICAL FORMULATION COMPRISING VORICONAZOLE | Glenmark Pharmaceuticals Limited (IN) | 2011-04-06 | — | — | EP | disclosed |
| WO-2010084505-A2 | STABLE TOPICAL FORMULATION COMPRISING VORICONAZOLE | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2010-07-29 | — | — | WO | disclosed |
| EP-1865896-A1 | ENHANCEMENT OF MACROLIDE PENETRATION THROUGH HUMAN SKIN | MacroChem Corporation (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-1999020257-A1 | HORMONE REPLACEMENT THERAPY DRUG FORMULATIONS FOR TOPICAL APPLICATION TO THE SKIN | MACROCHEM CORPORATION (US) | 1999-04-29 | — | — | WO | disclosed |
| EP-0552879-B1 | Improved iontophoretic administration of drugs | MACROCHEM CORP (US) | 1998-08-19 | — | — | EP | disclosed |
| US-5620980-A | TOPICALLY APPLYING MINOXIDIL AND PENETRATION ENHANCING AMOUNT OF 2-ALKYL-1,3-DIOXOLANE TO SKIN | MACROCHEM CORPORATION (US) | 1997-04-15 | — | — | US | disclosed |
| EP-0728462-A2 | Cosmetic method and composition for treating hair loss | MacroChem Corporation (US) | 1996-08-28 | — | — | EP | disclosed |
| US-5527797-A | IONTOPHORESIS | MACROCHEM CORPORATION (US) | 1996-06-18 | — | — | US | disclosed |
| EP-0552879-A1 | Improved iontophoretic administration of drugs | MACROCHEM CORPORATION (US) | 1993-07-28 | — | — | EP | disclosed |
| EP-0268460-B1 | NEW PERCUTANEOUS ABSORPTION ENHANCERS, COMPOSITIONS CONTAINING SAME AND METHOD OF USE | Macrochem Corporation (US) | 1991-11-06 | — | — | EP | disclosed |
| US-4861764-A | Percutaneous absorption enhancers, compositions containing same and method of use | MACRO CHEM. CORP. (US) | 1989-08-29 | — | — | US | disclosed |
| EP-0268460-A1 | New percutaneous absorption enhancers, compositions containing same and method of use | Macrochem Corporation (US) | 1988-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250195409-A1 | METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES | CNR2, CNR1, FAAH | ALDH1A1 1320/4885EPHX1 817/4885SPHK1 211/4885 |
| US-20110105448-A1 | Stable Topical Formulation Comprising Voriconazole | ERG28, CYP51A1, PIK3C3 | ALDH1A1 4022/4885EPHX1 3530/4885SPHK1 82/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.