Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.37 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15794261 | 0.82 | PIK3CA (0.35) | LIPEPRKAA2PIK3CA | |
| SCHEMBL15793967 | 0.82 | PIK3CA (0.35) | LIPEPRKAA2PIK3CA | |
| SCHEMBL15793513 | 0.82 | PIK3CA (0.35) | LIPEPRKAA2PIK3CA | |
| SCHEMBL15799412 | 0.82 | PIK3CA (0.35) | LIPEPRKAA2PIK3CA | |
| SCHEMBL15793956 | 0.82 | PIK3CA (0.35) | LIPEPRKAA2PIK3CA | |
| SCHEMBL14833871 | 0.82 | TRPV6 (0.43) | DRD4 | |
| SCHEMBL14815076 | 0.82 | TRPV6 (0.43) | DRD4 | |
| SCHEMBL15794006 | 0.81 | HRH3 (0.39) | KDM4EPOLBLIPEHRH3LMNA | |
| SCHEMBL15799494 | 0.81 | HRH3 (0.39) | KDM4EPOLBLIPEHRH3LMNA | |
| SCHEMBL15793634 | 0.81 | HRH3 (0.39) | KDM4EPOLBLIPEHRH3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029361-B2 | Agents for treating pain and uses thereof | ABBVIE INC. (US) | 2015-05-12 | — | — | US | disclosed |