SCHEMBL16690263

SCHEMBL16690263

CC(=O)O/N=C(\C)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.60
MAPT P10636 4/20 0.55
PKM P14618 1/20 0.54
CDK5 Q00535 1/20 0.54
CDK5R1 Q15078 1/20 0.54
S1PR1 P21453 1/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
MAPK1 P28482 2/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
PDCD1 Q15116 1/20 0.46
CD274 Q9NZQ7 1/20 0.46
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46
ALDH1A1 P00352 1/20 0.46
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14667470 0.89 MAPT (0.60) SMN1; SMN2MAPTPKMCDK5CDK5R1
SCHEMBL11963959 0.89 MAPT (0.60) SMN1; SMN2MAPTPKMCDK5CDK5R1
SCHEMBL212911 0.89 MAPT (0.60) SMN1; SMN2MAPTPKMCDK5CDK5R1
SCHEMBL4318071 0.83 SMN1; SMN2 (0.54) SMN1; SMN2MAPTPKMCDK5CDK5R1
SCHEMBL13626448 0.83 SMN1; SMN2 (0.54) SMN1; SMN2MAPTPKMCDK5CDK5R1
SCHEMBL16690274 0.83 SMN1; SMN2 (0.57) SMN1; SMN2MAPTL3MBTL1MAPK1PDCD1
SCHEMBL17973405 0.81 SMN1; SMN2 (0.55) SMN1; SMN2MAPTL3MBTL1MAPK1PDCD1
SCHEMBL9962632 0.81 HPGD (0.59) SMN1; SMN2MAPTPKMCDK5CDK5R1
SCHEMBL13626630 0.81 HTR1A (0.61) SMN1; SMN2MAPTPKMCDK5CDK5R1
SCHEMBL4311261 0.81 HTR1A (0.61) SMN1; SMN2MAPTPKMCDK5CDK5R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015064958-A1 NOVEL OXIME ESTER BIPHENYL COMPOUND, PHOTO INITIATOR AND PHOTOSENSITIVE RESIN COMPOSITION CONTAINING SAME 한국화학연구원 2015-05-07 WO disclosed