Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4318071 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTPKMCDK5CDK5R1 | |
| SCHEMBL16690263 | 0.83 | SMN1; SMN2 (0.60) | SMN1; SMN2MAPTPKMCDK5CDK5R1 | |
| SCHEMBL4311261 | 0.76 | HTR1A (0.61) | SMN1; SMN2MAPTPKMCDK5CDK5R1 | |
| SCHEMBL13626630 | 0.76 | HTR1A (0.61) | SMN1; SMN2MAPTPKMCDK5CDK5R1 | |
| SCHEMBL13626252 | 0.73 | PPARG (0.48) | SMN1; SMN2MAPTTDP1 | |
| SCHEMBL4321530 | 0.73 | PPARG (0.48) | SMN1; SMN2MAPTTDP1 | |
| SCHEMBL14667470 | 0.72 | MAPT (0.60) | SMN1; SMN2MAPTPKMCDK5CDK5R1 | |
| SCHEMBL11963959 | 0.72 | MAPT (0.60) | SMN1; SMN2MAPTPKMCDK5CDK5R1 | |
| SCHEMBL212911 | 0.72 | MAPT (0.60) | SMN1; SMN2MAPTPKMCDK5CDK5R1 | |
| SCHEMBL4060036 | 0.71 | ALDH1A1 (0.47) | SMN1; SMN2MAPTPKMALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009138416-A1 | OXIME CARBAMOYL DERIVATIVES AS MODULATORS OF FATTY ACID AMIDES HYDROLASE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-11-19 | — | — | WO | disclosed |