Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15426620 | 0.85 | — | — | |
| SCHEMBL18638681 | 0.83 | — | — | |
| SCHEMBL15427363 | 0.77 | PRKCI (0.41) | — | |
| SCHEMBL16692496 | 0.62 | PRKCI (0.51) | KCNJ1 | |
| SCHEMBL11623144 | 0.60 | MKNK1 (0.39) | — | |
| SCHEMBL11623137 | 0.59 | S100A4 (0.36) | — | |
| SCHEMBL30064747 | 0.58 | CCR1 (0.44) | — | |
| SCHEMBL11622684 | 0.58 | NOS3 (0.32) | — | |
| SCHEMBL100857 | 0.57 | DGAT1 (0.38) | — | |
| SCHEMBL11621375 | 0.55 | PDE3B (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343298-B1 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | INCYTE CORP (US) | 2015-05-06 | — | — | EP | disclosed |