SCHEMBL16692158

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16692216	0.91	TLR7 (0.49)	TLR7ENPP3ENPP1CA12CA1
	SCHEMBL16692144	0.87	TLR7 (0.48)	TLR7CA12CA1CA2CA9
	SCHEMBL10019146	0.86	TLR7 (0.43)	TLR7CA12CA1CA2CA9
	SCHEMBL16692187	0.85	TLR7 (0.46)	TLR7ENPP3ENPP1CA1CA2
	SCHEMBL16692201	0.84	TLR7 (0.48)	TLR7CA12CA1CA2CA9
	SCHEMBL13632792	0.83	TLR7 (0.42)	TLR7ENPP3ENPP1CA1CA2
	SCHEMBL20276025	0.83	CA12 (0.33)	TLR7CA12CA1CA2CA9
	SCHEMBL16692157	0.81	KDM4E (0.43)	TLR7ENPP3ENPP1CA12CA1
	SCHEMBL16692159	0.81	PDE10A (0.51)	TLR7CA12CA1CA2CA9
	SCHEMBL16692160	0.81	ALDH1A1 (0.56)	CA1CA2KDM4EHDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.