SCHEMBL16692191

SCHEMBL16692191

Cn1c(-c2cc3ccccc3cc2-c2nc3ccccc3n2C)nc2ccccc21

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.64
NPC1 O15118 8/20 0.64
RAB9A P51151 8/20 0.64
MEN1 O00255 4/20 0.57
KMT2A Q03164 4/20 0.57
ALDH1A1 P00352 8/20 0.56
TP53 P04637 5/20 0.56
GAA P10253 5/20 0.56
PKM P14618 4/20 0.56
HSD17B10 Q99714 4/20 0.56
ALOX15 P16050 1/20 0.56
SMN1; SMN2 Q16637 7/20 0.54
HPGD P15428 6/20 0.54
MAPT P10636 4/20 0.54
LMNA P02545 2/20 0.54
CYP3A4 P08684 1/20 0.53
MAPK1 P28482 1/20 0.53
HTT P42858 1/20 0.53
GFER P55789 1/20 0.53
USP2 O75604 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16692186 0.86 ALDH1A1 (0.67) KDM4ENPC1RAB9AMEN1KMT2A
SCHEMBL16692177 0.85 ALDH1A1 (0.65) KDM4ENPC1RAB9AMEN1KMT2A
SCHEMBL16692182 0.85 ALDH1A1 (0.65) KDM4ENPC1RAB9AMEN1KMT2A
SCHEMBL1171430 0.84 MEN1 (0.69) KDM4ENPC1RAB9AMEN1KMT2A
SCHEMBL16692202 0.84 KDM4E (0.59) KDM4ENPC1RAB9AMEN1KMT2A
SCHEMBL16692192 0.84 MEN1 (0.56) KDM4ENPC1RAB9AMEN1KMT2A
SCHEMBL16692167 0.82 MEN1 (0.54) KDM4ENPC1RAB9AMEN1KMT2A
SCHEMBL12648806 0.81 MEN1 (0.57) KDM4ENPC1RAB9AMEN1KMT2A
SCHEMBL16692197 0.81 MEN1 (0.57) KDM4ENPC1RAB9AMEN1KMT2A
SCHEMBL9976897 0.81 KDM4E (0.53) KDM4ENPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11362280-B2 Organic light-emitting device LG CHEM, LTD. (KR) 2022-06-14 US disclosed
US-11342508-B2 Organic light-emitting device LG CHEM, LTD. (KR) 2022-05-24 US disclosed
EP-2749560-B1 Novel nitrogen-containing heterocyclic compounds and organic electronic device using same LG CHEMICAL LTD (KR) 2019-10-02 EP disclosed
EP-3434670-A1 NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING SAME LG Chem, Ltd. (KR) 2019-01-30 EP disclosed
US-20180175302-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2018-06-21 US disclosed
US-20180175302-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2018-06-21 US disclosed
US-9666812-B2 Nitrogen-containing heterocyclic compound and organic electronic device using same LG CHEM, LTD. (KR) 2017-05-30 US disclosed
US-9666812-B2 Nitrogen-containing heterocyclic compound and organic electronic device using same LG CHEM, LTD. (KR) 2017-05-30 US disclosed
US-20150123089-A1 NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING SAME LG CHEM, LTD. (KR) 2015-05-07 US disclosed
US-20150123089-A1 NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING SAME LG CHEM, LTD. (KR) 2015-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150123089-A1 NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING SAME ODC1, OR10J3, NPM1 KDM4E 740/4885NPC1 3751/4885RAB9A 2896/4885
US-11342508-B2 Organic light-emitting device CRY1, CRY2, NR2E3 KDM4E 2028/4885NPC1 3639/4885RAB9A 3546/4885
US-20180175302-A1 ORGANIC LIGHT-EMITTING DEVICE CRY1, CRY2, NR2E3 KDM4E 2028/4885NPC1 3639/4885RAB9A 3546/4885
US-11362280-B2 Organic light-emitting device CRY1, CRY2, NR2E3 KDM4E 2028/4885NPC1 3639/4885RAB9A 3546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.